89501-90-6

Basic information

• Product Name: 1-METHYL-1H-PYRAZOLE-3-SULFONYL CHLORIDE
• Synonyms: 1-METHYL-1H-PYRAZOLE-3-SULFONYL CHLORIDE;1H-Pyrazole-3-sulfonyl chloride, 1-methyl-
• CAS NO: 89501-90-6
• Molecular Formula: C₄H₅ClN₂O₂S
• Molecular Weight: 180.6127
• Mol File: 89501-90-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 295.672 °C at 760 mmHg
• Flash Point: 132.618 °C
• Appearance: /
• Density: 1.605 g/cm³
• Vapor Pressure: 0.003mmHg at 25°C
• Refractive Index: 1.622
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -3.70±0.10(Predicted)
• CAS DataBase Reference: 1-METHYL-1H-PYRAZOLE-3-SULFONYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-METHYL-1H-PYRAZOLE-3-SULFONYL CHLORIDE(89501-90-6)
• EPA Substance Registry System: 1-METHYL-1H-PYRAZOLE-3-SULFONYL CHLORIDE(89501-90-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36
• Safety Statements: 26
• RIDADR: UN1759
• Hazardous Substances Data: 89501-90-6(Hazardous Substances Data)

Usage

Uses

1-Methyl-1H-pyrazole-3-sulfonyl Chloride is a reagent used in the synthesis of glucokinase activators which potently activate glucokinase in enzyme and cell assays.

InChI:InChI=1/C4H5ClN2O2S/c1-7-3-2-4(6-7)10(5,8)9/h2-3H,1H3

Upstream product

• 1904-31-0 methyl-1 amino-3 pyrazole 

Downstream Products

• 1213702-33-0 1-methyl-1H-pyrazole-3-sulfonic acid (4-chloro-benzyl)-(3-hydroxy-phenyl)-amide 
• 1383480-65-6 N-{3-[7-(1-{3-(Cyanomethyl)-1-[(1-methyl-1H-pyrazol-3-yl)sulfonyl]azetidin-3-yl}-1H-pyrazol-4-yl)imidazo[1,2-b]pyridazin-3-yl]phenyl}-N'-(2,2,2-trifluoroethyl)urea 
• 1257583-32-6 6-[benzyl-(1-methyl-1H-pyrazole-3-sulfonyl)-amino]-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester 
• 1256961-28-0 1-methyl-1H-pyrazole-3-sulfonic acid benzyl-(1-oxo-1,2,3,4-tetrahydro-isoquinolin-6-yl)-amide 
• 1256961-01-9 1-methyl-1H-pyrazole-3-sulfonic acid (4-chloro-benzyl)-(1-oxo-1,2,3,4-tetrahydro-isoquinolin-7-yl)-amide 
• 1214251-52-1 3-[(4-chloro-benzyl)-(1-methyl-1H-pyrazole-3-sulfonyl)-amino]-benzoic acid tert-butyl ester 
• 88398-97-4 1-methyl-1H-pyrazole-3-sulfonamide 

Relevant articles and documents

NLRP3 INHIBITORS

The present application relates to compounds with NLRP3inhibitory activity and to associated salts, solvates, prodrugs and pharmaceutical compositions. The present application further relates to the use of such compounds in the treatment and prevention of medical disorders and diseases, most especially by NLRP3inhibition.

Herbicidal diazoles sulfonamides

This invention relates to herbicidal heterocyclic aminocarbonyl diazole sulfonamides compounds, compositions thereof and a method for their use to control the growth of undesired vegetation.