89524-98-1

Basic information

• Product Name: (+/-)-BOC-ALPHA-PHOSPHONOGLYCINE TRIMETHYL ESTER
• Synonyms: (+/-)-BOC-ALPHA-PHOSPHONOGLYCINE TRI-;N-(tert-Butoxycarbonyl)-phosphonoglycinetrimethylester;(±)-boc-α-phosphonoglycine trimethyl ester;(±)-trimethyl-boc-α-phosphonoglycinate;(±)-Boc-a-phosphonoglycine trimethyl ester;(±)-Boc-ɑ-phosphonoglycine trimethyl ester, 95%;Methyl N-Boc-2-(dimethylphosphono)glycinate;N-tert-Butyloxycarbonyl-alpha-phosphonoglycine trimethyl ester
• CAS NO: 89524-98-1
• Molecular Formula: C10H20NO7P
• Molecular Weight: 297.24
• Mol File: 89524-98-1.mol
• Article Data: 17

Chemical Properties

• Melting Point: 67-71°C
• Boiling Point: 398.6 °C at 760 mmHg
• Flash Point: 194.9 °C
• Appearance: White to off-white/Powder or Crystalline Powder
• Density: 1.204 g/cm³
• Vapor Pressure: 1.46E-06mmHg at 25°C
• Refractive Index: 1.446
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• PKA: 9.63±0.46(Predicted)
• Water Solubility: Insoluble in water.
• BRN: 4296364
• CAS DataBase Reference: (+/-)-BOC-ALPHA-PHOSPHONOGLYCINE TRIMETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-BOC-ALPHA-PHOSPHONOGLYCINE TRIMETHYL ESTER(89524-98-1)
• EPA Substance Registry System: (+/-)-BOC-ALPHA-PHOSPHONOGLYCINE TRIMETHYL ESTER(89524-98-1)

Safety Data

• Hazard Codes: T
• Statements: 25
• Safety Statements: 45
• RIDADR: UN 2811 6.1/PG 3
• WGK Germany: 3
• F: 10
• HazardClass: 6.1
• PackingGroup: Ⅲ
• Hazardous Substances Data: 89524-98-1(Hazardous Substances Data)

Usage

Chemical Properties

White solid

Uses

Different sources of media describe the Uses of 89524-98-1 differently. You can refer to the following data:
1. Wittig-Horner reagent for preparing (Z)-Boc-protected dehydroamino acid derivatives.
2. It is used as Wittig-Horner reagent for preparing (Z)-Boc-protected dehydroamino acid derivatives and saturated, unnatural amino acids by subsequent asymmetric hydrogenation.

InChI:InChI=1/C10H20NO7P/c1-10(2,3)18-9(13)11-7(8(12)15-4)19(14,16-5)17-6/h7H,1-6H3,(H,11,13)/t7-/m1/s1

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 89537-21-3 methyl 2-amino-2-(dimethoxyphosphoryl)acetate 
• 4530-20-5 BOC-glycine 
• 128-08-5 N-Bromosuccinimide 
• 100945-15-1 N-(benzyloxycarbonyl)phosphonoglycine trimethyl ester 
• 150749-03-4 methyl 2-(tert-butoxycarbonylamino)-2-hydroxyacetate 
• 121-45-9 phosphorous acid trimethyl ester 
• 4248-19-5 tert-butyl carbazate 
• 60190-78-5 methyl 2-diazo-2-(dimethoxyphosphoryl)acetate 

Downstream Products

• 135582-89-7 methyl (R,Z)-4-benzyloxy-2-tert-butoxycarbonylamino-5-hydroxy-2-pentenoate 
• 1259394-66-5 (Z)-methyl 2-[(tert-butoxycarbonyl)amino]-3-(3,5-dimethoxyphenyl)acrylate 
• 135638-41-4 (R)-3-benzyloxycarbonyl-5-<(Z)-2-(tert-butoxycarbonylamino)-2-(methoxycarbonyl)vinyl>-2,2-dimethyl-1,3-oxazolidine 
• 134038-75-8 (R)-3-benzyloxycarbonyl-5-<(E)-2-(tert-butoxycarbonylamino)-2-(methoxycarbonyl)vinyl>-2,2-dimethyl-1,3-oxazolidine 
• 1418287-34-9 1-tert-butyl 2-methyl 4-chloro-1H-pyrrolo[3,2-c]pyridine-1,2-dicarboxylate 

Relevant articles and documents

Preparation method of Wittig-Horner reagent

A preparation method of a Wittig-Horner reagent is disclosed. According to the preparation method of the Wittig-Horner reagent provided by the invention, a compound with a structure as shown in a formula (I) and a glyoxylic acid aqueous solution with a sp

PEPTIDE NUCLEIC ACID MONOMERS AND OLIGOMERS

The invention relates to new peptide nucleic acid monomers and peptide nucleic acid oligomers comprising a dialkylamine side chain substituted with phosphonic acid ester group(s) or phosphonic acid group(s), and to the uses thereof.

Synthesis of the octahydroindole unit of aeruginosins via asymmetric hydrogenation of the Diels-Alder adducts of 2-amido-2,4-pentadienoate

An optically active octahydroindole, the core unit of aeruginosins (Choi) was synthesized. The Diels-Alder reaction of Danishefsky's diene with methyl (Z)-2-acetamido-2,4-pentadienoates provided the adducts regioselectively in good yield. The adducts were