895581-98-3

Basic information

• Product Name: 2-chloro-1-[(3-phenylselanyl)propyl]-1H-benzo[d]imidazole
• Synonyms: 2-chloro-1-[(3-phenylselanyl)propyl]-1H-benzo[d]imidazole
• CAS NO: 895581-98-3
• Molecular Weight: 349.721
• Mol File: 895581-98-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-chloro-1-[(3-phenylselanyl)propyl]-1H-benzo[d]imidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-1-[(3-phenylselanyl)propyl]-1H-benzo[d]imidazole(895581-98-3)
• EPA Substance Registry System: 2-chloro-1-[(3-phenylselanyl)propyl]-1H-benzo[d]imidazole(895581-98-3)

Safety Data

• Hazardous Substances Data: 895581-98-3(Hazardous Substances Data)

Upstream product

• 4857-06-1 2-chloro-1H-benzoimidazole 
• 122184-76-3 1-iodo-3-(phenylselanyl)propane 

Downstream Products

• 895582-01-1 4-({1-[(3-phenylselanyl)propyl]-1H-benzo[d]imidazol-2-yl}sulfanyl)benzoic acid 
• 7724-48-3 2,3-dihydro-1H-pyrrolo[1,2-a]benzimidazole 
• 80841-35-6 2-chloro-1-propyl-1H-benzo[d]imidazole 

Relevant articles and documents

Aromatic homolytic substitution using solid phase synthesis

Solid phase synthesis has been used to carry out intramolecular aromatic homolytic substitution with benzoimidazole precursors. The protocol attaches the radical precursors to the resins via the radical leaving groups (in the aromatic homolytic substitution). When the radical reactions are complete, the leaving group, unaltered starting material and reduced uncylised products remain attached to the resin, which facilitates easy separation of the cyclised products. Novel use of focussed microwave irradiation in solid phase radical reactions drastically shortens the reactions times. Tributylgermanium hydride has been used to replace the toxic and troublesome tributyltin hydride in the radical reactions.