89586-98-1

Basic information

• Product Name: 1H-1,5-Benzodiazepine, 2,4-bis(4-chlorophenyl)-2,3-dihydro-2-methyl-
• CAS NO: 89586-98-1
• Molecular Formula: C22H18Cl2N2
• Molecular Weight: 381.304
• Mol File: 89586-98-1.mol
• Article Data: 31

Chemical Properties

• Melting Point: 160-163 °C(Solv: ethanol (64-17-5))
• Boiling Point: 511.0±50.0 °C(Predicted)
• Density: 1.24±0.1 g/cm3(Predicted)
• CAS DataBase Reference: 1H-1,5-Benzodiazepine, 2,4-bis(4-chlorophenyl)-2,3-dihydro-2-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-1,5-Benzodiazepine, 2,4-bis(4-chlorophenyl)-2,3-dihydro-2-methyl-(89586-98-1)
• EPA Substance Registry System: 1H-1,5-Benzodiazepine, 2,4-bis(4-chlorophenyl)-2,3-dihydro-2-methyl-(89586-98-1)

Safety Data

• Hazardous Substances Data: 89586-98-1(Hazardous Substances Data)

Upstream product

• 99-91-2 para-chloroacetophenone 
• 95-54-5 1,2-diamino-benzene 
• 873-73-4 4-n-chlorophenylacetylene 
• 1516-58-1 o-azidonitrobenzene 

Downstream Products

• 1176196-29-4 (2S,4S)-2,4-bis(4-chlorophenyl)-2-methyl-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepine 
• 1176196-04-5 (2S,4R)-2,4-bis(4-chlorophenyl)-2-methyl-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepine 

Relevant articles and documents

A green and sustainable approach for the synthesis of 1,5-benzodiazepines and spirooxindoles in one-pot using a MIL-101(Cr) metal-organic framework as a reusable catalyst

Metal-organic framework MIL-101(Cr) has been efficiently utilized for the synthesis of biologically relevant heterocycles such as 1,5-benzodiazepines and spirooxindoles in one-pot. MIL-101(Cr) was prepared via a solvothermal method and characterized by FT

Assessment of elementary derivatives of 1,5-benzodiazepine as anticancer agents with synergy potential

Herein, we designed and synthesized 1,5-benzodiazepines as a lead molecule for anticancer activity and as potent synergistic activity with drug Methotrexate. Working under the framework of green chemistry principles, series of 1,5-benzodiazepine derivativ

One-pot, water-mediated, H2O2-HCl catalyzed synthesis of benzazepines

One-pot, multicomponent H2O2-HCl catalyzed system was employed for the synthesis of a series of benzazepine compounds. The implemented procedure oxidized the carbon-nitrogen bonds and produced benzazepines, while integrating diamines and substituted keton