89724-32-3

Basic information

• Product Name: 2-Cyclohexyl-4-carboxymethyl-5-methyloxazole
• Synonyms: 2-Cyclohexyl-4-carboxymethyl-5-methyloxazole
• CAS NO: 89724-32-3
• Molecular Weight: 223.272
• Mol File: 89724-32-3.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 2-Cyclohexyl-4-carboxymethyl-5-methyloxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Cyclohexyl-4-carboxymethyl-5-methyloxazole(89724-32-3)
• EPA Substance Registry System: 2-Cyclohexyl-4-carboxymethyl-5-methyloxazole(89724-32-3)

Safety Data

• Hazardous Substances Data: 89724-32-3(Hazardous Substances Data)

Upstream product

• 61152-00-9 2-cyclohexyl-5-methyl-oxazole-4-carboxylic acid ethyl ester 
• 61152-04-3 2-cyclohexyl-5-methyl-oxazole-4-carboxylic acid 
• 51655-86-8 2-cyclohexyl-5-methyl-oxazole-4-carbonyl chloride 
• 89744-48-9 (S)-2-(Cyclohexanecarbonyl-amino)-succinic acid 4-methyl ester 
• 107367-85-1 (S)-3-(Cyclohexanecarbonyl-amino)-4-oxo-pentanoic acid methyl ester 
• 136058-64-5 4-chloromethyl-2-cyclohexyl-5-methyl-oxazole 
• 89724-31-2 2-Cyclohexyl-4-hydroxymethyl-5-methyloxazole 
• 61151-95-9 2-cyclohexanecarbonylamino-3-oxo-butyric acid ethyl ester 
• 401791-01-3 3-(cyclohexanecarbonyl-amino)-4-oxo-pentanoic acid benzyl ester 
• 2719-27-9 cyclohexanylcarbonyl chloride 
• 108192-92-3 (2-cyclohexyl-5-methyl-oxazol-4-yl)acetonitrile 
• 401791-02-4 (2-cyclohexyl-5-methyl-oxazol-4-yl)-acetic acid benzyl ester 

Downstream Products

• 132646-47-0 2-(2-cyclohexyl-5-methyl-oxazol-4-yl)-ethanol 

Relevant articles and documents

SUBSTITUTED 4-ALKOXYOXAZOL DERIVATIVES AS PPAR AGONISTS

The present invention relates to compounds of formula (I) wherein R1 to R8 and n are as defined in the description and claims, and pharmaceutically acceptable salts and esters thereof. The compounds are useful for the treatment of diseases such as diabetes.

Application of the Dakin-West reaction for the synthesis of oxazole-containing dual PPARα/γ agonists

An improved method for the preparation of a series of oxazole-containing dual PPARα/γ agonists is described. A synthetic sequence utilizing a Dakin-West reaction was devised that allows for the introduction of the oxazole ring either late in the synthetic sequence via aminomalonate-derived chemistry or in pivotal SAR intermediates derived from aspartic acid.

Oxazolidinedione hypoglycemic agents

Compounds of the formulae where R is cycloalkyl or aryl; R1 is alkyl, X is O or C=O; A is O or S; and B is N or CH are useful as hypoglycemic agents.