897384-03-1

Basic information

• Product Name: N-(3-chloro-4-(pyridin-2-ylmethoxy)phenyl)-7-methoxy-6-nitroquinazoline-4-amine
• Synonyms: N-(3-chloro-4-(pyridin-2-ylmethoxy)phenyl)-7-methoxy-6-nitroquinazoline-4-amine
• CAS NO: 897384-03-1
• Molecular Weight: 437.842
• Mol File: 897384-03-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: N-(3-chloro-4-(pyridin-2-ylmethoxy)phenyl)-7-methoxy-6-nitroquinazoline-4-amine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-chloro-4-(pyridin-2-ylmethoxy)phenyl)-7-methoxy-6-nitroquinazoline-4-amine(897384-03-1)
• EPA Substance Registry System: N-(3-chloro-4-(pyridin-2-ylmethoxy)phenyl)-7-methoxy-6-nitroquinazoline-4-amine(897384-03-1)

Safety Data

• Hazardous Substances Data: 897384-03-1(Hazardous Substances Data)

Upstream product

• 162012-69-3 7-fluoro-6-nitro-3H-quinazolin-4-one 
• 1012057-47-4 7-methoxy-6-nitroquinazolin-4(3H)-one 
• 55496-69-0 4-chloro-7-methoxy-6-nitroquinazoline 
• 524955-09-7 3-chloro-4-(2-pyridylmethoxy)aniline 
• 1194097-41-0 2-amino-4-fluoro-5-nitrobenzoic acid 
• 619-08-9 2-chloro-4-nitrophenol 
• 162012-69-3 7-fluoro-6-nitro-4-hydroxyquinazoline 
• 162012-70-6 4-chloro-7-fluoro-6-nitroquinazoline 
• 897441-42-8 N-(3-chloro-4-(pyridin-2-ylmethoxy)phenyl)-7-fluoro-6-nitroquinazolin-4-amine 
• 124-41-4 sodium methylate 

Downstream Products

• 897384-05-3 (2S)-pyrrolidine-2-carboxylic acid {4-[3-chloro-4-(pyridin-2-ylmethoxy)-phenylamino]-7-methoxy-quinazolin-6-yl}-amide 

Relevant articles and documents

QUINAZOLINE DERIVATIVE AND PREPARATION METHOD THEREFOR

The present invention relates to a quinazoline derivative shown in formula (I) and a preparation method therefor, a pharmaceutical composition comprising the compound shown in formula (I), and an application of the compound in preparing drugs for curing and preventing tumors. The compound of the present invention can irreversibly prevent EGFR phosphorylation, and effectively depress signal transduction of cancer cells, and accordingly has higher anti-tumor activity in vitro and in vivo,

AMINOQUINAZOLINE DERIVATIVES AND THEIR SALTS AND METHODS OF USE THEREOF

Provided herein are aminoquinazoline compounds, salts and uses thereof. The compounds have Formula (I), or a stereoisomer, a geometric isomer, a tautomer, an N-oxide, a hydrate, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug ther

QUINAZOLINE DERIVATIVES FOR INHIBITING CANCER CELL GROWTH AND METHOD FOR THE PREPARATION THEREOF

The present invention relates to a novel quinazoline derivative and a pharmaceutically acceptable salt thereof for inhibiting the growth of cancer cells, a method for the preparation thereof and a pharmaceutical composition comprising same as an active ingredient.