90-76-6

Basic information

• Product Name: 2-amino-2-deoxy-D-galactopyranose
• Synonyms: 2-Amino-2-deoxy-D-galactopyranose; 7535-00-4; D-Chondrosamine; D-galactopyranose, 2-amino-2-deoxy-; Galactopyranose, 2-amino-2-deoxy-, D-; GalN
• CAS NO: 90-76-6
• Molecular Formula: C₆H₁₃NO₅
• Molecular Weight: 179.1711
• Mol File: 90-76-6.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 449.9°C at 760 mmHg
• Flash Point: 225.9°C
• Density: 1.563g/cm³
• Vapor Pressure: 5.53E-10mmHg at 25°C
• Refractive Index: 1.6
• PKA: 12.27±0.70(Predicted)
• CAS DataBase Reference: 2-amino-2-deoxy-D-galactopyranose(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-2-deoxy-D-galactopyranose(90-76-6)
• EPA Substance Registry System: 2-amino-2-deoxy-D-galactopyranose(90-76-6)

Safety Data

• Hazardous Substances Data: 90-76-6(Hazardous Substances Data)

Upstream product

• 57-48-7 D-Fructose 
• 24967-94-0 dermatan sulfate 
• 24967-93-9 chondroitin sulfate 
• 9050-30-0 heparan sulfate 
• 9005-49-6 heparin 
• 1415305-18-8 4,6-dimethoxy-1,3,5-triazin-2-yl β-D-galactosamine hydrochloride 
• 9004-61-9 hyaluronic acid 
• 1415305-17-7 4,6-dimethoxy-1,3,5-triazin-2-yl β-D-glucosamine hydrochloride 
• 7284-16-4 p-nitrophenyl 2-acetamido-2-deoxy-β-D-glucopyranosyl-(1→4)-2-acetamido-2-deoxy-β-D-glucopyranoside 
• 91032-39-2 C₆₆H₅₈Cl₂N₈O₂₃ 
• 29886-32-6 β-D-GlcpNAc(1->4)-D-GlcNAc-ol 
• 111286-55-6 2-deoxy-2-<(4,4-dimethyl-2,6-dioxocyclohexylidenemethyl)amino>-α,β-D-glucopyranose 
• 107-18-6 allyl alcohol 
• 16405-05-3 2-acetamido-1-N-(1-benzyloxy-N-benzyloxycarbonyl-4-L-aspartyl)-2-deoxy-β-D-glucopyranosylamine 

Downstream Products

• 6857-22-3 N-(2,4,5-trihydroxy-6-hydroxymethyl-tetrahydropyran-3-yl)butyramide 
• 79698-60-5 Imidazole-1-sulfonic acid (2R,4aR,6S,7R,8R,8aR)-7-benzyloxycarbonylamino-6-methoxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yl ester 
• 10022-13-6 1,3,4,6-tetra-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranose 
• 488-32-4 dextro-d-ribohexosamic acid 
• 3006-60-8 1,3,4,6-tetra-O-acetyl-2-acetamido-2-deoxy-α,β-D-mannopyranose 
• 112578-78-6 2-acetamido-3,4,5,6-tetra-O-acetyl-2-deoxy-D-galactose diethyl dithioacetal 
• 4239-72-9 ethyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-1-thio-β-D-galactopyranoside 
• 134122-76-2 (4R)-1-p-chlorophenyl-5-hydroxy-4-(D-arabino-tetritol-1-yl)imidazolidine-2-thione 
• 3006-58-4 2-carbobenzyloxyamino-2-deoxy-D-galactopyranose 
• 13032-89-8 2-benzamido-1,3,4,6-tetra-O-benzoyl-2-deoxy-α-D-galactopyranose 
• 13032-90-1 2-benzamido-1,3,4,6-tetra-O-benzoyl-2-deoxy-β-D-galactopyranose 
• 14307-03-0 2-amino-2-deoxy-D-glucitol 
• 3646-68-2 D-glucosaminic acid 
• 75-47-8 iodoform 

Relevant articles and documents

Acidolysis-based component mapping of glycosaminoglycans by reversed-phase high-performance liquid chromatography with off-line electrospray ionization-tandem mass spectrometry: Evidence and tags to distinguish different glycosaminoglycans

Diverse monosaccharide analysis methods have been established for a long time, but few methods are available for a complete monosaccharide analysis of glycosaminoglycans (GAGs) and certain acidolysis- resistant components derived from GAGs. In this report, a reversed-phase high-performance liquid chromatography (RP-HPLC) method with pre-column 1-phenyl-3-methyl-5-pyrazolone (PMP) derivatization was established for a complete monosaccharide analysis of GAGs. Good separation of glucosamine/ mannosamine (GlcN/ManN) and glucuronic acid/iduronic acid (GlcA/IdoA) was achieved. This method can also be applied to analyze the acidolysis-resistant disaccharides derived from GAGs, and the sequences of these disaccharides were confirmed by electrospray ionization-collision-induced dissociation- tandem mass spectrometry (ESI-CID-MS/MS). These unique disaccharides could be used as markers to distinguish heparin/heparan sulfate (HP/HS), chondroitin sulfate/dermatan sulfate (CS/DS), and hyaluronic acid (HA).

CHONDROITIN COMPLEXES FOR TRANSCUTANEOUS ABSORPTION

The present invention relates to the use of chondroitin as a transdermal carrier and slow-release system for active ingredients in pharmaceutical and cosmeceutical compositions.

4,6-dimethoxy-1,3,5-triazin-2-yl-d-glycosaminides: Novel substrates for transglycosylation reaction catalyzed by exo-d-glucosaminidase from amycolatopsis orientalis

A novel sugar adduct, 4,6-dimethoxy-1,3,5-triazin-2-yl-d-glucosaminide (GlcN-DMT), has been prepared by the reaction of d-glucosamine (GlcN) and 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-morpholinium chloride (DMT-MM). The adduct was recognized by exo-d-glucosaminidase (GlcNase) from Amycolatopsis orientalis and transferred the GlcN moiety, giving rise to the corresponding glucosaminides. This chemo-enzymatic process was successfully applied to d-galactosamine (GalN). GalN-DMT prepared directly from GalN and DMT-MM behaved as an efficient glycosyl donor for transfer of the GalN moiety catalyzed by the same enzyme. The introduction of the 4,6-dimethoxy-1,3,5-triazin-2-yl leaving group to the anomeric center significantly enhanced transglycosylating ability, resulting in the efficient glycosidase-catalyzed synthesis of glycosaminides.