90000-67-2

Basic information

• Product Name: 2,6-dimethyl-1H-pyridine-4-thione
• Synonyms: 2,6-dimethyl-1H-pyridine-4-thione
• CAS NO: 90000-67-2
• Molecular Formula: C7H9NS
• Molecular Weight: 139.22
• Mol File: 90000-67-2.mol
• Article Data: 3

Chemical Properties

• Melting Point: 224 °C(Solv: water (7732-18-5))
• Boiling Point: 191.8°Cat760mmHg
• Flash Point: 69.8°C
• Appearance: /
• Density: 1.11g/cm³
• Vapor Pressure: 0.506mmHg at 25°C
• Refractive Index: 1.595
• PKA: 2.42±0.15(Predicted)
• CAS DataBase Reference: 2,6-dimethyl-1H-pyridine-4-thione(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-dimethyl-1H-pyridine-4-thione(90000-67-2)
• EPA Substance Registry System: 2,6-dimethyl-1H-pyridine-4-thione(90000-67-2)

Safety Data

• Hazardous Substances Data: 90000-67-2(Hazardous Substances Data)

Usage

Type of compound

heterocyclic organic compound

Structure

contains a pyridine ring with a thione substitution at the 4-position

Usage

commonly used as a reagent in organic synthesis

Odor

has a strong odor

Potential uses

studied for its potential use in pharmaceuticals and agrochemicals due to its interesting biological activities

Other potential uses

investigated for its potential as a corrosion inhibitor and as a complexing agent in analytical chemistry.

InChI:InChI=1/C7H9NS/c1-5-3-7(9)4-6(2)8-5/h3-4H,1-2H3,(H,8,9)

Upstream product

• 3512-75-2 4-chloro-2,6-lutidine 
• 2402-78-0 2,6-dichloropyridine 
• 42051-83-2 4-Hydroxy-2,6-dimethyl-pyridin-N-oxid 
• 4808-64-4 4-nitro-2,6-lutidine-1-oxide 
• 1073-23-0 2,6-lutidine N-oxide 
• 108-48-5 2,6-dimethylpyridine 
• 1004-37-1 2,6-dimethyl-pyran-4-thione 
• 64-17-5 ethanol 
• 7664-41-7 ammonia 
• 7783-06-4 hydrogen sulfide 
• 13603-44-6 2,6-dimethylpyridin-4-ol 

Downstream Products

• 89776-80-7 2,6-Lutidin-4-sulfonsaeure 

Relevant articles and documents

KETONE INHIBITORS OF LYSINE GINGIPAIN

The present invention provides compounds according to Formula (I) as described herein, and their use for inhibiting the lysine gingipain protease (Kgp) from the bacterium Porphyromonas gingivalis. Also described are gingipain activity probe compounds and methods for assaying gingipain activity are also described, as well as methods for the treatment of disorders associated with P. gingivalis infection, including brain disorders such as Alzheimer's disease.

Novel nevirapine-like inhibitors with improved activity against NNRTI-resistant HIV: 8-Heteroarylthiomethyldipyridodiazepinone derivatives

A series of 8-heteroarylthiomethyldipyridodiazepinone derivatives were prepared and evaluated for their antiviral profile against wild type virus and the important K103N/Y181C mutant as an indicator for broad activity. 2,6-Dimethylpyridine derivative 16 was found to have a good pharmacokinetic profile in spite of poor metabolic stability in rat liver microsomes.