90037-24-4

Basic information

• Product Name: 4(1H)-Pyridinone, 2-methyl-3-(phenylmethoxy)-1-propyl-
• CAS NO: 90037-24-4
• Molecular Formula: C16H19NO2
• Molecular Weight: 257.332
• Mol File: 90037-24-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 4(1H)-Pyridinone, 2-methyl-3-(phenylmethoxy)-1-propyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 4(1H)-Pyridinone, 2-methyl-3-(phenylmethoxy)-1-propyl-(90037-24-4)
• EPA Substance Registry System: 4(1H)-Pyridinone, 2-methyl-3-(phenylmethoxy)-1-propyl-(90037-24-4)

Safety Data

• Hazardous Substances Data: 90037-24-4(Hazardous Substances Data)

Upstream product

• 61049-69-2 3-O-benzylmaltol 
• 100-44-7 benzyl chloride 
• 107-10-8 propylamine 
• 118-71-8 Maltol 

Downstream Products

• 1219111-79-1 3-Benzyloxy-1-(propyl)-pyridin-4(1H)-one-2-carboxaldehyde 
• 30652-13-2 3-hydroxy-2-methyl-1-propyl-4(1H)-pyridinone 

Relevant articles and documents

PROCESS FOR THE PREPARATION OF SUBSTITUTED PYRIDONE CARBOXYLIC ACIDS

The present invention relates to methods for the preparation of pyridone carboxylic acids for use as intermediates in the preparation of various synthetic organic compounds. The pyridone carboxylic acids can for example be used as intermediates in the production of potent antitumor agents, antifungal agents, antiviral agents, psychotherapeutic agents or contrast imaging agents for MRI.

Synthesis, physicochemical properties, and biological evaluation of N- substituted 2-alkyl-3-hydroxy-4(1H)-pyridinones: Orally active iron chelators with clinical potential

The synthesis of a range of novel bidentate ligands containing the chelating moiety 3-hydroxy-4(1H)-pyridinone is described. The pK(a) values of the ligands and the stability constants of their iron(III) complexes have been determined. The crystal structures of one of the ligands and one of the iron(III) complexes are presented. The distribution coefficients of the ligands are reported and are related to the ability of the ligands to remove iron from hepatocytes. The influence of 3-hydroxy-4(1H)-pyridinones on oxidative damage to cells is described. In contrast to the iron chelator in current therapeutic use, desferrioxamine-B, many of the bidentate ligands described in this study are orally active in iron-overloaded mice.