9007-73-2 Usage
Uses
Different sources of media describe the Uses of 9007-73-2 differently. You can refer to the following data:
1. Tool for the study of protein synthesis and regulatory mechanisms.
2. Ferritin, cationized from horse spleen has been used:to incubate amoebae (106) in the study, to determine whether trophozoites are able to take up ferritin and internalise this protein for their growth in axenic cultureto determine phagosome-lysosome fusion by electron microscopyto label freshly excised chick optic tecta in serum free incubation medium
3. Ferritin from human liver has been used as model protein in size-exclusion high-performance liquid chromatography technique and for synthetic nanopore translocation studies. It has also been used to test its effect on the susceptibility of shrimp (Litopenaeus vannamei) to the white spot syndrome virus.
General Description
Ferritin, an iron-storage protein is usually present in the liver and spleen in mammals. Iron and?ferritin?are distributed relatively same in the eye. Ferritin is made up of heavy and light chains.
Biochem/physiol Actions
Ferritin holds iron at its ferric state (Fe3+). The core of ferritin?has the capability to hold 4500 iron molecules. It is essential to store iron in vertebrates. Ferritin?is also essential to store and transport iron in invertebrates. It plays a key role in dietary iron absorption.
Purification Methods
The purification of this major iron-binding protein is achieved by homogenisation in water and precipitation with ammonium sulfate, repeating the cycle of ultracentrifugation, and molecular sieve chromatography through a Sephadex 4B column. Isoelectric focusing reveals a broad spectrum of impurities which can be separated by ion-exchange chromatography on Sephadex A-25 and stepwise elution. [Konijn et al. Anal Biochem 144 423 1985.]
Check Digit Verification of cas no
The CAS Registry Mumber 9007-73-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 9,0,0 and 7 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 9007-73:
(6*9)+(5*0)+(4*0)+(3*7)+(2*7)+(1*3)=92
92 % 10 = 2
So 9007-73-2 is a valid CAS Registry Number.
