90145-22-5

Basic information

• Product Name: 1H-Pyrazole-4-carboxylic acid, 1-methyl-3-phenyl-, methyl ester
• CAS NO: 90145-22-5
• Molecular Formula: C12H12N2O2
• Molecular Weight: 216.239
• Mol File: 90145-22-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1H-Pyrazole-4-carboxylic acid, 1-methyl-3-phenyl-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrazole-4-carboxylic acid, 1-methyl-3-phenyl-, methyl ester(90145-22-5)
• EPA Substance Registry System: 1H-Pyrazole-4-carboxylic acid, 1-methyl-3-phenyl-, methyl ester(90145-22-5)

Safety Data

• Hazardous Substances Data: 90145-22-5(Hazardous Substances Data)

Usage

Derivative

Methyl ester derivative of 1-methyl-3-phenyl-1H-pyrazole-4-carboxylic acid

Common Usage

Building block in organic synthesis

Potential Applications

Pharmaceutical industry
Agrochemical industry

Reactivity

Versatile

Precursor For

Various functionalized pyrazole derivatives

Handling

Requires careful handling
Adherence to safety guidelines essential

Hazards

Potential health risks
Environmental hazards if mishandled

Upstream product

• 90145-13-4 N'-<α-bromobenzylidene>-N-methylhydrazinium bromide 
• 13466-29-0 1-benzylidene-2-methylhydrazine 
• 96256-52-9 3-Phenyl-4-trifluoromethyl-1H-pyrazole 
• 772-62-3 3,3,3-trifluoro-1-phenylpropyne 
• 4891-38-7 phenylpropynoic acid methyl ester 
• 256658-45-4 C₅H₁₄N₂OSi 
• 922-67-8 propynoic acid methyl ester 
• 90145-21-4 1-Methyl-3-phenyl-2-pyrazolin-4-carbonsaeure-methylester 
• 186581-53-3 diazomethane 
• 21031-22-1 methyl 3-phenyl-1H-pyrazole-4-carboxylate 
• 637-44-5 phenylpropyolic acid 

Relevant articles and documents

Novel generation of azomethine imines from α-silylnitrosamines by 1,4- silatropic shift and their cycloaddition

Novel and facile generation of azomethine imines from α- silylnitrosamines and subsequent cycloaddition with dipolarophiles leading to a variety of pyrazole derivatives have been developed. The key to the reaction is a 1,4-silatropic shift caused by stron

Studies on Organic Fluorine Compounds. XLII. Synthesis and Reactions of Phenyltrifluoromethylacetylenes

Phenyltrifluoromethylacetylene (4a) was synthesized by the pyrolysis of triphenylphosphonium α-(trifluoroacetyl)benzylide (3a), which was easily derived from benzyl halide (1a).This method can be used for the synthesis of 4-substituted-phenyltrifluoromethylacetylenes (4).The 1,3-dipolar reaction of 4 with diazomethane and phenyl azide proceeds readily to give trifluoromethylated pyrazoles and triazoles.Keywords - trifluoromethyl; acetylene; 1,3-dipolar reaction; intramolecular Wittig reaction; trifluoroacetylphosphonium ylide; pyrazole; diazomethane; phenyl azide