90252-91-8

Basic information

• Product Name: 1,3-Benzenedicarboxylic acid, 2-hydroxy-4-(2-phenylethenyl)-, dimethyl ester
• CAS NO: 90252-91-8
• Molecular Formula: C18H16O5
• Molecular Weight: 312.322
• Mol File: 90252-91-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1,3-Benzenedicarboxylic acid, 2-hydroxy-4-(2-phenylethenyl)-, dimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Benzenedicarboxylic acid, 2-hydroxy-4-(2-phenylethenyl)-, dimethyl ester(90252-91-8)
• EPA Substance Registry System: 1,3-Benzenedicarboxylic acid, 2-hydroxy-4-(2-phenylethenyl)-, dimethyl ester(90252-91-8)

Safety Data

• Hazardous Substances Data: 90252-91-8(Hazardous Substances Data)

Upstream product

• 1830-54-2 3-oxopentanedioic acid dimethyl ester 
• 42457-27-2 (E)-5-(2-phenylethyl)isoxazole 
• 75513-43-8 1-(dimethylamino)-5-phenylpenta-1,4-dien-3-on 
• 1896-62-4 (E)-benzalacetone 
• 75513-43-8 (1E, 4E)-1-(dimethylamino)-5-phenylpenta-1, 4-dien-3-one 

Relevant articles and documents

SYNTHESES OF (+)- AND (-)-MELLEIN UTILIZING AN ANNELATION REACTION OF ISOXAZOLES WITH DIMETHYL 3-OXOGLUTARATE

Naturally occurring dihydroisocoumarins, (+)- and (-)-mellein (2 and 3), metabolites of fungals, Cercospora sp. and Aspergillus sp., etc., were synthesized from the isoxazoles (32) and (33) by the annelation reactions with dimethyl 3-oxoglutarate.

A New Aromatic Annelation Reaction with Two Synthons, Enaminones and 3-Oxoglutarate. Studies on the β-Carbonyl Compounds Connected with β-Polyketides. VIII

Reactions of the enaminones 1 with dimethyl 3-oxoglutarate in the presence of KF-AcOH or AcONa-AcOH and 18-crown-6 gave the dimethyl 2-hydroxy-1,3-benzenedicarboxylates 3, providing a new aromatic annelation reaction.Keywords - enaminone; dimethyl 3-oxoglutarate; buffer catalysis; aromatic annelation; dimethyl 2-hydroxy-1,3-benzenedicarboxylate