90254-19-6Relevant articles and documents
Development of a practical Buchwald-Hartwig amine arylation protocol using a conveniently prepared (NHC)Pd(R-allyl)Cl catalyst
Cawley, Mark J.,Cloke, F. Geoffrey N.,Fitzmaurice, Richard J.,Pearson, Stuart E.,Scott, James S.,Caddick, Stephen
, p. 2820 - 2825 (2008)
Continuing efforts to establish a more general "user-friendly" protocol for the palladium-catalysed arylation of amines (Buchwald-Hartwig reaction) are described herein. Significant advances have been made through the use of the versatile (SIPr)Pd(methallyl)Cl complex in conjunction with the reliable base lithium hexamethyldisilazide (LHMDS). The Royal Society of Chemistry.