903513-62-2

Basic information

• Product Name: (2-AMINO-4-PYRIDYL)BORONIC ACID
• Synonyms: (2-AMINO-4-PYRIDYL)BORONIC ACID;2-aminopyridin-4-ylboronic acid;2-Aminopyridine-4-boronic acid;2-aMino-4-pyridinyl boronic acid;(2-Aminopyridin-4-yl)
• CAS NO: 903513-62-2
• Molecular Formula: C₅H₇BN₂O₂
• Molecular Weight: 137.93
• EINECS: 1533716-785-6
• Product Categories: 6
• Mol File: 903513-62-2.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 411.7±55.0 °C(Predicted)
• Appearance: /
• Density: 1.33±0.1 g/cm3(Predicted)
• Storage Temp.: Keep in dark place,Sealed in dry,Store in freezer, under -20°C
• PKA: 5.74±0.10(Predicted)
• CAS DataBase Reference: (2-AMINO-4-PYRIDYL)BORONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (2-AMINO-4-PYRIDYL)BORONIC ACID(903513-62-2)
• EPA Substance Registry System: (2-AMINO-4-PYRIDYL)BORONIC ACID(903513-62-2)

Safety Data

• Hazardous Substances Data: 903513-62-2(Hazardous Substances Data)

Usage

General Description

(2-Amino-4-Pyridyl)boronic Acid is a chemical compound that belongs to the class of boronic acids and their derivatives. It is characterized by the presence of a boronic acid core structure. This chemical is also known for its role as an organoboron compound, which is a subclass of boron-containing organic compounds that contain carbon-boron a bond directly connecting the boron atom to a carbon atom. It is often used in scientific experiments and research, notably in the field of chemistry, for its special properties related to its structure, such as its affinity for diols, which can be exploited in various chemical reactions and processes. As with any chemical compound, (2-Amino-4-Pyridyl)boronic Acid must be handled with care due to potential risks and hazardous properties.

Upstream product

• 84249-14-9 2-amino-4-bromopyridine 
• 73183-34-3 bis(pinacol)diborane 
• 19798-80-2 2-Amino-4-chloropyridine 

Downstream Products

• 1150542-85-0 2-(2-aminopyridin-4-yl)-3-(3-chloro-4-fluorophenyl)-1H-pyrrolo[3,2-b]pyridine-5-carbonitrile 
• 1258311-32-8 C₂₃H₂₄N₆O₂ 
• 1368227-63-7 4-(3-aminophenyl)pyridin-2-amine 
• 1240523-34-5 C₂₅H₂₈N₄O₃ 
• 1240523-35-6 C₂₄H₂₃N₅OS 

Relevant articles and documents

REV-ERB AGONISTS FOR THE TREATMENT OF TH17-MEDIATED INFLAMMATORY DISORDERS

The present disclosure provides compounds of Formula IA and Formula IB and their pharmaceutical compositions as selective agonists of REV-ERB-α: where R1, R2, R3, R4, R5, RX1, RX2, nA, nB, X, Y, and Z are described herein. The compounds are useful in various methods and uses, such as in the treatment of diseases including hyperglycemia, dyslipidemia, atherosclerosis, and autoimmune and inflammatory disorders or diseases, and as cancer therapeutics, such as for the treatment of glioblastoma, hepatocellular carcinoma, and colorectal cancer, and for immune-oncology purposes.

FARNESOID X RECEPTOR AGONISTS AND USES THEREOF

Described herein are compounds that are farnesoid X receptor agonists, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with farnesoid X receptor activity.

Syntheses of novel 2,3-diaryl-substituted 5-cyano-4-azaindoles exhibiting c-Met inhibition activity

Herein we report the syntheses of 2,3-diaryl-substituted pyrrolo[3,2-b]pyridine-5-carbonitriles via a one-pot 5-endo-dig-cyclization/protection reaction followed by palladium catalyzed arylation. In addition, a complementary synthesis route employing Laro