90356-00-6

Basic information

• Product Name: Propanamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methyl-3-(phenylthio)-
• CAS NO: 90356-00-6
• Molecular Formula: C18H15F3N2O2S
• Molecular Weight: 380.391
• Mol File: 90356-00-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Propanamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methyl-3-(phenylthio)-(CAS DataBase Reference)
• NIST Chemistry Reference: Propanamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methyl-3-(phenylthio)-(90356-00-6)
• EPA Substance Registry System: Propanamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methyl-3-(phenylthio)-(90356-00-6)

Safety Data

• Hazardous Substances Data: 90356-00-6(Hazardous Substances Data)

Upstream product

• 108-98-5 thiophenol 
• 90357-51-0 N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide 
• 112988-42-8 2-Hydroxy-2-methyl-3-phenylsulfanyl-propionitrile 
• 5042-53-5 1-(phenylsulfanyl)acetone 
• 90357-22-5 α-hydroxy-β-phenylsulfanyl-isobutyric acid 
• 654-70-6 4-amino-2-trifluoromethylbenzonitrile 

Downstream Products

• 90357-05-4 N-[4-cyano-3-(trifluoromethyl)phenyl]-3-(phenyl)sulfonyl-2-hydroxy-2-methyl-propanamide 
• 90356-93-7 3-Benzenesulfinyl-N-(4-cyano-3-trifluoromethyl-phenyl)-2-hydroxy-2-methyl-propionamide 

Relevant articles and documents

Synthesis of potential impurities of bicalutamide

Bicalutamide is an oral nonsteroidal, anti-androgen drug used for prostate cancer. It binds to the androgen receptor. During the bulk synthesis of bicalutamide, various impurities are formed. The present work details the development of simple processes for the preparation of impurities of bicalutamide, viz bical-sulfoxides (6), bical-deshydroxy (10), bical-desfluoro (10a), bical-2-fluoro (10b), and bical-3-fluoro (10c). Copyright Taylor & Francis Group, LLC.