90366-21-5

Basic information

• Product Name: 2(5H)-Furanone, 5-phenyl-, (5R)-
• CAS NO: 90366-21-5
• Molecular Formula: C10H8O2
• Molecular Weight: 160.172
• Mol File: 90366-21-5.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 2(5H)-Furanone, 5-phenyl-, (5R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2(5H)-Furanone, 5-phenyl-, (5R)-(90366-21-5)
• EPA Substance Registry System: 2(5H)-Furanone, 5-phenyl-, (5R)-(90366-21-5)

Safety Data

• Hazardous Substances Data: 90366-21-5(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 2243-53-0 trans-styrylacetic acid 
• 122-78-1 phenylacetaldehyde 
• 96-09-3 styrene oxide 
• 2243-53-0 styrylacetic acid 
• 528609-61-2 (R)-((1S,2R,3S,4R)-3-Hydroxymethyl-bicyclo[2.2.1]hept-5-en-2-yl)-phenyl-methanol 
• 591-51-5 phenyllithium 
• 20780-53-4 (R)-Styrene oxide 
• 79-22-1 methyl chloroformate 
• 74-88-4 methyl iodide 
• 528609-80-5 (1R,2S,5R,6R,7S)-5-Phenyl-4-oxa-tricyclo[5.2.1.0^2,6]dec-8-en-3-one 
• 246862-25-9 (S)-2-(4-methyl-2,6,7-trioxabicyclo[2,2,2]oct-1-yl)ethyl 2,4,6-triisopropylphenyl sulfoxide 
• 90366-20-4 (+)-(3R,4S,R_S)-4-phenyl-3-(p-tolylsulphinyl)-γ-butyrolactone 
• 1008-76-0 γ-phenyl-γ-butyrolactone 

Relevant articles and documents

A Chiral Electrophilic Selenium Catalyst for Highly Enantioselective Oxidative Cyclization

Chiral electrophilic selenium catalysts have been applied to catalytic asymmetric transformations of alkenes over the past two decades. However, highly enantioselective reactions with a broad substrate scope have not yet been developed. We report the first successful example of this reaction employing a catalyst based on a rigid indanol scaffold, which can be easily synthesized from a commercially available indanone. The reaction efficiently converts β,γ-unsaturated carboxylic acids into various enantioenriched γ-butenolides under mild conditions.

A facile solid-phase synthesis of substituted 2(5H)-furanones with sulfone traceless linker

A novel solid-phase synthetic method for substituted 2(5H)-furanones with traceless sulfone linker strategy has been developed. The products were obtained in good yields and excellent purities.

A convergent asymmetric synthesis of γ-butenolides

The addition of aldehydes to the new enantiomerically pure lithiated sulfoxide-orthoester 13 yielded γ-butenolides of high enantiomeric purities after elimination of phenylsulfinic acid. The cyclocondensation with ketones was less stereoselective. This new asymmetric synthesis of γ-butenolides has been applied to a convergent preparation of the antifungal antibiotic (+)-cerulenin.