90403-98-8Relevant articles and documents
Synthesis and evaluation of mefway analogs as ligands for serotonin 5HT1A receptors
Thio, Joanne P.,Liang, Christopher,Bajwa, Alisha K.,Wooten, Dustin W.,Christian, Bradley T.,Mukherjee, Jogeshwar
, p. 1480 - 1486 (2015/04/27)
18F-Mefway (N-{2-[4-(2′methoxyphenyl)piperazinyl]ethyl}-N-(2-pyridyl)-N-(4′18F-fluoro-methylcyclohexane)carboxamide) was developed and evaluated for use as a PET ligand for imaging 5-HT1A receptors. Ongoing studies of sup
1,2,4 -TRIAZOLES AS ALLOSTERIC MODULATORS OF MGLU5 RECEPTOR ACTIVITY FOR THE TREATMENT OF SCHIZOPHRENIA OF DEMENTIA
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Page/Page column 89, (2013/06/27)
This invention relates to compounds of formula (I) their use as positive allosteric modulators of mGlu5 receptor activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of neurological and psychiatric disorders associated with glutamate dysfunction such as schizophrenia or cognitive decline such as dementia or cognitive impairment. A, B, X, R1, R2, R3 have meanings given in the description.
Synthesis of new chiral pyrylium salts and their phosphinine and pyridine derivatives
Van Der Velde, Nelson A.,Korbitz, Holland T.,Garner, Charles M.
supporting information, p. 5742 - 5744 (2012/11/06)
Despite their versatility, chiral pyryliums are almost unknown in the literature. Reported here is the synthesis of several new chiral pyrylium salts and the corresponding pyridines and phosphinines. This work more than doubles the number of reported chir