905-96-4

Basic information

• Product Name: 3 3'-DIETHYLOXACARBOCYANINE IODIDE 98
• Synonyms: 3 3'-DIETHYLOXACARBOCYANINE IODIDE 98;3-ethyl-2-[3-(3-ethyl-3H-benzoxazol-2-ylidene)prop-1-enyl]benzoxazolium iodide;3,3'-DIETHYLOXACARBOCYANINE IODIDE, FOR FLUORESCENCE;3 3'-DIETHYLOXACARBOCYANINE IODIDE 98%;3,3''-Diethyl-2,2''-oxacarbocyanine iodide;DiOC2(3), DOC Iodide, 3-Ethyl-2-[3-(3-ethyl-2(3H)-benzoxazolylidene)-1-propenyl]benzoxazolium iodide;2-[3-(2,3-Dihydro-3-ethylbenzoxazole-2-ylidene)-1-propenyl]-3-ethylbenzoxazole-3-ium·iodide;2-[3-[3-Ethylbenzoxazole-2(3H)-ylidene]-1-propenyl]-3-ethylbenzoxazole-3-ium·iodide
• CAS NO: 905-96-4
• Molecular Formula: C₂₁H₂₁N₂O₂*I
• Molecular Weight: 460.30811
• EINECS: 212-996-6
• Product Categories: Cyanine
• Mol File: 905-96-4.mol
• Article Data: 1

Chemical Properties

• Melting Point: 278 °C (dec.)(lit.)
• Appearance: Dark red/Powder
• Solubility: Soluble in methanol, dimethyl sulfoxide
• Sensitive: Light Sensitive
• CAS DataBase Reference: 3 3'-DIETHYLOXACARBOCYANINE IODIDE 98(CAS DataBase Reference)
• NIST Chemistry Reference: 3 3'-DIETHYLOXACARBOCYANINE IODIDE 98(905-96-4)
• EPA Substance Registry System: 3 3'-DIETHYLOXACARBOCYANINE IODIDE 98(905-96-4)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• TSCA: Yes
• Hazardous Substances Data: 905-96-4(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 905-96-4 differently. You can refer to the following data:
1. 3,3''-Diethyloxacarbocyanine Iodide is a fluorescent probe for measuring membrane potential. It has been used to analyze bacterial viability by flow cytometry using fluorescence emission ratio detection.
2. DiOC may be used as a conjugate for labelling cells for cytofluorometry studies . It may also be used in the imaging of carbon nanotubes(CNTs) using fluorescence microscopy. Staining of spermatozoa can potentially be done by DiOC which can be used in flow cytometric measurement and viability assay.

General Description

3,3′-Diethyloxacarbocyanine iodide(DiOC) is a cyanine based dye which is used in the photosensitization of mitochondria and endoplastic recticulum in animals and plant cells.

Upstream product

• 62-53-3 aniline 
• 122-51-0 orthoformic acid triethyl ester 
• 3724-43-4 Vilsmeier reagent 
• 5260-37-7 3-ethyl-2-methyl-1,3-benzoxazol-3-ium iodide 
• 14036-06-7 diethoxymethyl acetate 

Relevant articles and documents

MACROPHAGE IDENTIFICATION AGENT, AND IDENTIFICATION METHOD, SORTING METHOD, EVALUATION METHOD, SCREENING METHOD AND KIT USING THE MACROPHAGE IDENTIFIER AGENT

An object of the present invention is to provide an identification method for a macrophage subtype using an organic compound. Another object of the present invention is to provide a macrophage identification agent containing an organic compound in which a spectral characteristic obtained when the organic compound is added is different depending on a macrophage subtype. Still another object of the present invention is to provide an evaluation method for a macrophage subtype using a macrophage identification agent, an analysis method for correlation between a macrophage subtype and a test substance, a screening method for correlation between a macrophage subtype and a test substance, and a kit. An identification method for a macrophage subtype utilizing that a spectral characteristic obtained with an organic compound added is different depending on a macrophage subtype is provided.