90503-56-3

Basic information

• Product Name: AzithroMycin N-Oxide
• Synonyms: AzithroMycin N-Oxide
• CAS NO: 90503-56-3
• Molecular Formula: C9H18BrClSi
• Molecular Weight: 269.68
• Mol File: 90503-56-3.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: -20°C Freezer
• Solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
• CAS DataBase Reference: AzithroMycin N-Oxide(CAS DataBase Reference)
• NIST Chemistry Reference: AzithroMycin N-Oxide(90503-56-3)
• EPA Substance Registry System: AzithroMycin N-Oxide(90503-56-3)

Safety Data

• Hazardous Substances Data: 90503-56-3(Hazardous Substances Data)

Usage

Uses

Azithromycin N-Oxide (Azithromycin EP Impurity L) is an Azithromycin (A927000) impurity. A degradation products of Azithromycin.

Upstream product

• 75-77-4 chloro-trimethyl-silane 

Relevant articles and documents

TRIMETHYLSILYL- UND HALOGENSUBSTITUIERTE 2-METHYL-1-PENTENE

2-Methyl1-pentenes D, with Cl and/or Br substituted in positions 1 and 5 respectively, were synthesized for the first time, with 2-acetyl-γ-butyrolactone as the starting compound, and they reacted after either metallation with butyllithium or transformation into Grignard compounds with chlorotrimethylsilane to give the different trimethylsilyl- and halogen-substituted 2-methyl-1-pentenes L, M, N and P.Because of the Wittig reactions in the steps 3 + A B and E + A D, all the pentenes were obtained in their E/Z isomeric mixtures.The assignment of the NMRspectra to the E and Z form was made possible from investigating Van der Waals and nuclear Overhauser effects (NOE) in the 400 MHz spectra.Transformation of D into Grignard compounds is highly dependent on the character of the halogen in positions 1 or 5.