90505-36-5

Basic information

• Product Name: (S)-P1-(3-MERCAPTO-1-PYRROLIDINYL)ETHYLIDENE]-(4-NITROPHENYL)METHYL ESTER, CARBAMIC ACID
• Synonyms: (S)-P1-(3-MERCAPTO-1-PYRROLIDINYL)ETHYLIDENE]-(4-NITROPHENYL)METHYL ESTER, CARBAMIC ACID;(S)-[1-(3-Mercapto-1-pyrrolidinyl)ethylidene]carbamic acid (4-nitrophenyl)methyl ester;Side Chain of PanipeneM;S-(1-(1-((((4-nitrobenzyl)oxy)carbonyl)iMino)ethyl)pyrrolidin-3-yl) ethanethioate 4-Nitrobenzyl-1-((S)-3-Mercaptopyrrolidin-1-yl)ethylidenecarbaMate;Side Chain for PanipeneM;N-[1-[(3S)-3-Mercapto-1-pyrrolidinyl]ethylidene]carbamic Acid (4-Nitrophenyl)methyl Ester;Carbamic acid,N-[1-[(3S)-3-mercapto-1-pyrrolidinyl]ethylidene]-, (4-nitrophenyl)methyl ester
• CAS NO: 90505-36-5
• Molecular Formula: C₁₄H₁₇N₃O₄S
• Molecular Weight: 323.371
• EINECS: 1312995-182-4
• Mol File: 90505-36-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 549.007 °C at 760 mmHg
• Flash Point: 285.83 °C
• Appearance: /
• Density: 1.38
• PKA: 10.10±0.20(Predicted)
• CAS DataBase Reference: (S)-P1-(3-MERCAPTO-1-PYRROLIDINYL)ETHYLIDENE]-(4-NITROPHENYL)METHYL ESTER, CARBAMIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-P1-(3-MERCAPTO-1-PYRROLIDINYL)ETHYLIDENE]-(4-NITROPHENYL)METHYL ESTER, CARBAMIC ACID(90505-36-5)
• EPA Substance Registry System: (S)-P1-(3-MERCAPTO-1-PYRROLIDINYL)ETHYLIDENE]-(4-NITROPHENYL)METHYL ESTER, CARBAMIC ACID(90505-36-5)

Safety Data

• Hazardous Substances Data: 90505-36-5(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 90505-36-5 differently. You can refer to the following data:
1. (S)-[1-(3-Mercapto-1-pyrrolidinyl)ethylidene]carbamic acid (4-nitrophenyl)methyl ester is an intermediate used for the preparation of carbapenem antibiotic, a class of β-lactam antibiotics that exe rts a broad spectrum of antibacterial activity.
2. N-[1-[(3S)-3-Mercapto-1-pyrrolidinyl]ethylidene]carbamic Acid (4-Nitrophenyl)methyl Ester is an intermediate used for the preparation of carbapenem antibiotic, a class of β-lactam antibiotics that exerts a broad spectrum of antibacterial activity.

InChI:InChI=1/C14H17N3O4S/c18-14(19)15-13(16-8-7-12(22)9-16)6-3-10-1-4-11(5-2-10)17(20)21/h1-2,4-5,12,22H,3,6-9H2,(H,18,19)/p-1/b15-13-/t12-/m0/s1

Upstream product

• 4457-32-3 4-nitrobenzyl chloroformate 
• 90505-34-3 3-(R)-methanesulfonyloxy-1-(N-p-nitrobenzyloxycarbonylacetimidoyl)pyrrolidine 
• 90512-67-7 3-(R)-hydroxy-1-(N-p-nitrobenzyloxycarbonylacetimidoyl)pyrrolidine 
• 90505-35-4 3-(S)-acetylthio-1-(N-p-nitrobenzyloxycarbonylacetimidoyl)pyrrolidine 

Downstream Products

• 101135-08-4 (4S,5S,6S)-6-(1-Hydroxy-ethyl)-4-methyl-3-((S)-1-{1-[(E)-4-nitro-benzyloxycarbonylimino]-ethyl}-pyrrolidin-3-ylsulfanyl)-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester 
• 101135-09-5 1-α-methyl RS-533 
• 98167-65-8 {(2R,3S)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-4-oxo-azetidin-2-yl}-thioacetic acid S-((S)-1-{1-[(Z)-4-nitro-benzyloxycarbonylimino]-ethyl}-pyrrolidin-3-yl) ester 
• 101135-13-1 (5S,6S)-6-(1-Hydroxy-ethyl)-4-methoxy-3-((S)-1-{1-[(E)-4-nitro-benzyloxycarbonylimino]-ethyl}-pyrrolidin-3-ylsulfanyl)-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester 
• 97033-05-1 Trimethylsilanyl-thioacetic acid S-((S)-1-{1-[(E)-4-nitro-benzyloxycarbonylimino]-ethyl}-pyrrolidin-3-yl) ester 

Relevant articles and documents

SYNTHESIS OF OPTICALLY ACTIVE 3-MERCAPTOPYRROLIDINE DERIVATIVES. SYNTHETIC INTERMEDIATES OF CARBAPENEM RS-533 AND ITS ISOMER

The optically active 3-mercaptopyrrolidine derivatives(3a, 3b, 4a and 4b), which are synthetic intermediates of the carbapenem RS-533 (2a) and its isomer (2b), were synthesized by convenient and practical methods.