90724-57-5

Basic information

• Product Name: Pyrrole-2-carboxylic acid, 3-methyl- (6CI,7CI)
• Synonyms: Pyrrole-2-carboxylic acid, 3-methyl- (6CI,7CI);Pyrrole-2-carboxylic acid, 3-methyl-;3-Methyl-1H-pyrrole-2-carboxylicacid
• CAS NO: 90724-57-5
• Molecular Formula: C₆H₇NO₂
• Molecular Weight: 125.12
• Product Categories: PYRROLE
• Mol File: 90724-57-5.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 322.4 °C at 760 mmHg
• Flash Point: 148.8 °C
• Appearance: /
• Density: 1.295 g/cm³
• Vapor Pressure: 0.000115mmHg at 25°C
• Refractive Index: 1.586
• Storage Temp.: 2-8°C
• CAS DataBase Reference: Pyrrole-2-carboxylic acid, 3-methyl- (6CI,7CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrrole-2-carboxylic acid, 3-methyl- (6CI,7CI)(90724-57-5)
• EPA Substance Registry System: Pyrrole-2-carboxylic acid, 3-methyl- (6CI,7CI)(90724-57-5)

Safety Data

• Hazardous Substances Data: 90724-57-5(Hazardous Substances Data)

Usage

General Description

Pyrrole-2-carboxylic acid, 3-methyl- (6CI,7CI) is a chemical compound with the molecular formula C6H7NO2. It is a derivative of pyrrole, a heterocyclic compound with a five-membered ring containing one nitrogen atom. Pyrrole-2-carboxylic acid, 3-methyl- is a carboxylic acid derivative with a methyl group attached to the pyrrole ring at the 3-position. It is used in organic synthesis and as a building block for the preparation of various pharmaceuticals and agrochemicals. Pyrrole-2-carboxylic acid, 3-methyl- (6CI,7CI) has potential applications in the fields of medicinal chemistry and drug discovery due to its unique structure and properties.

InChI:InChI=1/C6H7NO2/c1-4-2-3-7-5(4)6(8)9/h2-3,7H,1H3,(H,8,9)

Upstream product

• 3284-47-7 ethyl 3-methyl-1H-pyrrole-2-carboxylate 
• 3284-53-5 3-methyl-1-p-toluenesulfonyl-2,5-dihydro-1H-pyrrole-2-carboxylic acid ethyl ester 
• 3284-52-4 ethyl 3-hydroxy-3-methyl-1-p-toluenesulfonylpyrrolidine-2-carboxylate 
• 40611-69-6 methyl 3-methyl-1H-pyrrole-2-carboxylate 
• 90610-57-4 3-methyl-pyrrole-2,4-dicarboxylic acid-2-ethyl ester 

Downstream Products

• 1403941-98-9 1-amino-3-methyl-N-(o-tolyl)-1H-pyrrole-2-carboxamide 

Relevant articles and documents

Synthesis process method of 3-substituted-1H-pyrrole

The invention provides a synthetic process method of a 3-substituted-1H-pyrrole compound. The process method comprises the following steps: by taking diethylamine hydrochloride and glycine ethyl esterhydrochloride as initial raw materials, respectively carrying out Mannich reaction and sulfamide reaction, and carrying out cyclization reaction, dehydration thinning reaction, aromatization reactionand hydrolysis decarboxylation reaction to obtain a 3-substituted-1H-pyrrole compound. According to the synthesis process method of the 3-substituted-1H-pyrrole compound, the whole synthesis route isgood in step repeatability, mild in operation condition and high in safety, and large-scale production and industrial popularization are facilitated; post-treatment energy consumption is low, a largeamount of toxic wastewater is not generated, no pollution is caused to the environment, the production safety level and the production cost are reduced, application of green and environment-friendlyindustrial production is facilitated, and wide application prospects are achieved.

Bromine structural domain inhibitor compound and application thereof

The invention relates to a bromine structural domain inhibitor and provides a compound shown in a general formula I, pharmaceutical salt, an enantiomer, a diastereoisomer, an atropisomer, racemate, apolymorphic substance and solvate of the compound or an isotope labelled compound (including a deuterium substituted compound), a preparation method of the compound, pharmaceutical composition containing the compound and an application of the above components in pharmaceuticals.

PYRROLOTRIAZINONE DERIVATIVES AS PI3K INHIBITORS

New pyrrolotriazinone derivatives having the chemical structure of formula (I), are disclosed; as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Phosphoinositide 3-Kinases (PI3Ks)