90806-58-9

Basic information

• Product Name: 5-methoxyisoquinoline
• Synonyms: 5-methoxyisoquinoline
• CAS NO: 90806-58-9
• Molecular Formula: C₁₀H₉NO
• Molecular Weight: 159.18
• EINECS: -0
• Mol File: 90806-58-9.mol
• Article Data: 22

Chemical Properties

• Boiling Point: 295.593 °C at 760 mmHg
• Flash Point: 108.428 °C
• Appearance: /
• Density: 1.131 g/cm³
• Vapor Pressure: 0.003mmHg at 25°C
• Refractive Index: 1.611
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 5.13±0.13(Predicted)
• CAS DataBase Reference: 5-methoxyisoquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 5-methoxyisoquinoline(90806-58-9)
• EPA Substance Registry System: 5-methoxyisoquinoline(90806-58-9)

Safety Data

• Hazardous Substances Data: 90806-58-9(Hazardous Substances Data)

Usage

General Description

5-methoxyisoquinoline is a chemical compound with the molecular formula C10H9NO2. It is a derivative of isoquinoline and contains a methoxy group attached to the 5-position of the isoquinoline ring. 5-methoxyisoquinoline is commonly used as a precursor in the synthesis of various pharmaceuticals and natural products. It has been studied for its potential biological activities, including its role as an antioxidant and its ability to inhibit the growth of certain cancer cells. Additionally, 5-methoxyisoquinoline has shown promise as a potential therapeutic agent for the treatment of neurodegenerative diseases such as Alzheimer's and Parkinson's disease. Further research is ongoing to fully understand the pharmacological properties and potential uses of this compound.

InChI:InChI=1/C10H9NO/c1-12-10-4-2-3-8-7-11-6-5-9(8)10/h2-7H,1H3

Upstream product

• 186581-53-3 diazomethane 
• 2439-04-5 5-hydroxyisoquinoline 
• 39964-88-0 N-(3-methoxybenzyl)-N-tosylaminoacetaldehyde dimethyl acetal 
• 67-56-1 methanol 
• 74-88-4 methyl iodide 
• 7732-18-5 water 
• 138-24-9 phenyltrimethylammonium chloride 
• 578-67-6 quinolin-5-ol 
• 40359-32-8 3-allyloxy-benzaldehyde 
• 100-83-4 meta-hydroxybenzaldehyde 
• 94956-98-6 2-allyl-3-methoxybenzaldehyde 

Downstream Products

• 103030-70-2 5-methoxy-1,2,3,4-tetrahydro-isoquinoline 
• 90806-60-3 5-methoxyisoquinoline-1-carbonitrile 

Relevant articles and documents

As neuroprotective agents of pharmaceutical compounds

The invention discloses a medicinal compound as a neuroprotective agent. The medicinal compound is a neuronal nitric oxide synthase-postsynaptic density protein 95 (nNOS-PSD95) decoupling agent. The medicinal compound is a benzene ring derivative shown in the general formula (I) or its pharmaceutically acceptable salt. The invention further discloses a preparation method of the medicinal compound and a use of the medicinal compound in prevention and treatment on neuronal damage influence-caused diseases.

HEPATITIS C VIRUS INHIBITORS

The present disclosure relates to compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.

HCV NS5A replication complex inhibitors. Part 4.1 optimization for genotype 1a replicon inhibitory activity

A series of symmetrical E-stilbene prolinamides that originated from the library-synthesized lead 3 was studied with respect to HCV genotype 1a (G-1a) and genotype 1b (G-1b) replicon inhibition and selectivity against BVDV and cytotoxicity. SAR emerging f