908141-95-7 Usage
General Description
4-(2-hydrazinopyrimidin-4-yl)morpholine, also known as MPTP, is a chemical compound that has been used in research to study the effects of Parkinson's disease. MPTP is known to be a neurotoxin that can cause symptoms similar to Parkinson's disease in humans and other primates. It is a potent inhibitor of mitochondrial function and can cause damage to the dopaminergic neurons in the brain, leading to a decrease in dopamine levels. This chemical has been utilized to create animal models of Parkinson's disease for studying the condition and developing potential treatments. However, due to its toxic effects, MPTP is not used in clinical treatments and is strictly controlled in research settings.
Check Digit Verification of cas no
The CAS Registry Mumber 908141-95-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,0,8,1,4 and 1 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 908141-95:
(8*9)+(7*0)+(6*8)+(5*1)+(4*4)+(3*1)+(2*9)+(1*5)=167
167 % 10 = 7
So 908141-95-7 is a valid CAS Registry Number.
908141-95-7Relevant articles and documents
Discovery of KDM5A inhibitors: Homology modeling, virtual screening and structure-activity relationship analysis
Wu, Xiaoai,Fang, Zhen,Yang, Bo,Zhong, Lei,Yang, Qiuyuan,Zhang, Chunhui,Huang, Shenzhen,Xiang, Rong,Suzuki, Takayoshi,Li, Lin-Li,Yang, Sheng-Yong
supporting information, p. 2284 - 2288 (2016/04/20)
Herein we report the discovery of a series of new KDM5A inhibitors. A three-dimensional (3D) structure model of KDM5A jumonji domain was firstly established based on homology modeling. Molecular docking-based virtual screening was then performed against c
