908575-58-6

Basic information

• Product Name: 3,4-O-isopropylidene-D-mannitol
• Synonyms: 3,4-O-isopropylidene-D-mannitol
• CAS NO: 908575-58-6
• Molecular Weight: 222.238
• Mol File: 908575-58-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3,4-O-isopropylidene-D-mannitol(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-O-isopropylidene-D-mannitol(908575-58-6)
• EPA Substance Registry System: 3,4-O-isopropylidene-D-mannitol(908575-58-6)

Safety Data

• Hazardous Substances Data: 908575-58-6(Hazardous Substances Data)

Upstream product

• 81704-51-0 1,2:3,4:5,6-tri-O-isopropylidene-galactitol 

Downstream Products

• 20196-69-4 1,2,5,6-tetra-O-benzyl-D-mannitol 
• 20258-50-8 1,2,5,6-tetra-O-benzyl-3,4-O-isopropylidene-D-mannitol 

Relevant articles and documents

SYNTHESIS OF PHOSPHATIDYL-β-GLUCOSYL GLYCEROL CONTAINING A DIOLEOLYL DIGLYCERIDE MOIETY. APPLICATION OF THE TETRAISOPROPYLDISILOXANE-1,3-DIYL (TIPS) PROTECTING GROUP IN SUGAR CHEMISTRY. PART IV

The preparation of phosphatidyl-β-glucosyl diglyceride 12c is described.The synthesis of glycophospholipid 12c was accomplished by using: (a) the levulinoyl group for the temporary protection of the glucose hydroxyl functions of 6b, which could then be converted into the dioleoyl substituted derivative 7c; (b) the tetraisopropyldisiloxane-1,3-diyl (TIPS) group to protect the 3'- and 4'-hydroxyl groups of 7c, in a two step procedure, to afford compound 8; (c) a 2,4-dichlorophenyl protected phosphatidic acid derivative 11.Compound 11 could be selectively coupled to the primary hydroxyl function of 8 to afford the fully protected glycophospholipid 12a.Finally, removal of the 2,4-dichlorophenyl and TIPS protecting groups from 12a was performed with syn-4-nitrobenzaldoximate and fluoride ions, respectively, to afford glycophospholipid 12c.