90946-21-7

Basic information

• Product Name: 4-Methyl-1-(4-nitrophenyl)-1H-imidazole
• Synonyms: 4-Methyl-1-(4-nitrophenyl)-1H-imidazole
• CAS NO: 90946-21-7
• Molecular Formula: C₁₀H₉N₃O₂
• Molecular Weight: 203.19736
• Mol File: 90946-21-7.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 385.9°C at 760 mmHg
• Flash Point: 187.2°C
• Appearance: /
• Density: 1.29g/cm³
• Vapor Pressure: 8.2E-06mmHg at 25°C
• Refractive Index: 1.634
• CAS DataBase Reference: 4-Methyl-1-(4-nitrophenyl)-1H-imidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Methyl-1-(4-nitrophenyl)-1H-imidazole(90946-21-7)
• EPA Substance Registry System: 4-Methyl-1-(4-nitrophenyl)-1H-imidazole(90946-21-7)

Safety Data

• Hazardous Substances Data: 90946-21-7(Hazardous Substances Data)

Usage

General Description

4-Methyl-1-(4-nitrophenyl)-1H-imidazole is a chemical compound that belongs to the class of organic compounds known as nitroimidazoles, specifically imidazole rings substituted with a nitro group. Imidazole is a five-membered planar ring, which has three carbon atoms and two nitrogen atoms at nonadjacent positions. The presence of the nitrophenyl group, which consists of a phenyl group attached to a nitro group, makes this chemical more reactive. 4-Methyl-1-(4-nitrophenyl)-1H-imidazole is primarily used in scientific research and has not been reported to occur naturally in significant quantities. Its exact metabolic and biological details are not commonly known, but like other imidazole derivatives, it might have potential for various applications in pharmaceuticals.

InChI:InChI=1/C10H9N3O2/c1-8-6-12(7-11-8)9-2-4-10(5-3-9)13(14)15/h2-7H,1H3

Upstream product

• 822-36-6 4-methyl-1H-imidazole 
• 100-00-5 4-chlorobenzonitrile 
• 586-78-7 para-nitrophenyl bromide 
• 350-46-9 4-Fluoronitrobenzene 

Downstream Products

• 102791-87-7 4-methyl-1-(4-aminophenyl)-1H-imidazole 
• 1201902-19-3 [6-(4-methyl-1H-imidazol-1-yl)-2-(phenyl)]quinoline 
• 1201902-62-6 3-ethoxy-N-[4-(4-methyl-1H-imidazol-1-yl)phenyl]acrylamide 
• 1300695-70-8 1,1-dimethylethyl (3-{[4-(4-methyl-1H-imidazol-1-yl)phenyl]amino}butanoyl)carbamate 

Relevant articles and documents

N-Heterocyclic Carbene Copper(I) Complex Catalyzed Coupling of (Hetero)aryl Chlorides and Nitrogen Heterocycles: Highly Efficient Catalytic System

A highly efficient catalytic system for the N-arylation reactions of (hetero)aryl chlorides and nitrogen heterocycles with a copper(I) complex containing a 1,10-phenanthroline analogue N-heterocyclic carbene (NHC) has been reported. The complex was characterized by 1H NMR and 13C NMR spectroscopy and elemental analysis, and its structure was determined by single-crystal X-ray diffraction. The NHC-copper(I) complex was employed as pre-catalyst for Ullmann type N-arylation reactions of (hetero)aryl chlorides with various azoles. A variety of hindered and functionalized azoles and (hetero)aryl chlorides were transformed in good to excellent yields.

FUSED MORPHOLINOPYRIMIDINES AND METHODS OF USE THEREOF

The present disclosure relates to Fused Morpholinopyrimidines, pharmaceutical compositions comprising an effective amount of a Fused Morpholinopyrimidine and methods for using a Fused Morpholinopyrimidine in the treatment of a neurodegenerative disease, comprising administering to a subject in need thereof an effective amount of a Fused Morpholinopyrimidine.

FUSED MORPHOLINOPYRIMIDINES AND METHODS OF USE THEREOF

The present disclosure relates to Fused Morpholinopyrimidines, pharmaceutical compositions comprising an effective amount of a Fused Morpholinopyrimidine and methods for using a Fused Morpholinopyrimidine in the treatment of a neurodegenerative disease, comprising administering to a subject in need thereof an effective amount of a Fused Morpholinopyrimidine.