910301-32-5

Basic information

• Product Name: 1,3-Difluoro-5-(4-nitrophenyl)benzene
• Synonyms: 1,3-Difluoro-5-(4-nitrophenyl)benzene
• CAS NO: 910301-32-5
• Molecular Formula: C12H7F2NO2
• Molecular Weight: 235.1862864
• Mol File: 910301-32-5.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,3-Difluoro-5-(4-nitrophenyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Difluoro-5-(4-nitrophenyl)benzene(910301-32-5)
• EPA Substance Registry System: 1,3-Difluoro-5-(4-nitrophenyl)benzene(910301-32-5)

Safety Data

• Hazardous Substances Data: 910301-32-5(Hazardous Substances Data)

Usage

Type of compound

Synthetic organic compound

Structure

Benzene ring with two fluorine atoms and a nitro group substitution

Applications

a. Building block for pharmaceuticals
b. Building block for agrochemicals
c. Building block for dyes
d. Fluorine-containing building block for new materials and functional molecules

Health and environmental hazards

Potential risks if not properly managed

Precautions

Handle with care and follow safety guidelines

Upstream product

• 636-98-6 p-nitrobenzene iodide 
• 156545-07-2 3,5-difluorophenylboronic acid 
• 100-00-5 4-chlorobenzonitrile 

Relevant articles and documents

A novel polymer containing phosphorus-nitrogen ligands for stabilization of palladium nanoparticles: An efficient and recyclable catalyst for Suzuki and Sonogashira reactions in neat water

A new polymer containing phosphorus and nitrogen ligands was successfully synthesized, characterized and used for the stabilization of highly monodispersed palladium nanoparticles having an average diameter of 2-3 nm. The thermally stable heterogeneous catalyst was successfully applied in Suzuki-Miyaura and copper-free Sonogashira-Hagihara coupling reactions of aryl halides under low palladium loading conditions. Reactions were proceeded in neat water without using any organic co-solvents. The catalyst was successfully recycled for the sample Suzuki-Miyaura reaction nine consecutive times with small drop in catalytic activity.

Self-supported heterogeneous star-shaped oxime-palladacycle catalysts for the Suzuki coupling reactions

A novel strategy to synthesize heterogeneous star-shaped oxime-palladacycle catalysts, which exhibited good catalytic activity and recyclability in the Suzuki coupling of aryl bromides and chlorides, was described. Georg Thieme Verlag Stuttgart.