911-60-4

Basic information

• Product Name: 1-(3,4-diethoxybenzyl)-6,7-diethoxy-3,4-dihydroisoquinolinium chloride
• CAS NO: 911-60-4
• Molecular Formula: C₂₄H₃₂ClNO₄
• Molecular Weight: 433.9682
• Mol File: 911-60-4.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 527°C at 760 mmHg
• Flash Point: 217.7°C
• Vapor Pressure: 1.14E-10mmHg at 25°C
• CAS DataBase Reference: 1-(3,4-diethoxybenzyl)-6,7-diethoxy-3,4-dihydroisoquinolinium chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3,4-diethoxybenzyl)-6,7-diethoxy-3,4-dihydroisoquinolinium chloride(911-60-4)
• EPA Substance Registry System: 1-(3,4-diethoxybenzyl)-6,7-diethoxy-3,4-dihydroisoquinolinium chloride(911-60-4)

Safety Data

• Hazardous Substances Data: 911-60-4(Hazardous Substances Data)

Usage

Chemical class

Quaternary ammonium compounds

Structure

Quaternary ammonium salt with a diethoxybenzyl group attached to the nitrogen atom and diethoxy substituents on the isoquinolinium ring

Applications

a. Organic synthesis
b. Preparation of other quaternary ammonium salts
c. Synthesis of pharmaceuticals and organic compounds

Potential use

Reactive agent in the field of organic chemistry

Properties

a. Reactivity
b. Valuable tool for research and development

Industries

a. Chemical
b. Pharmaceutical

Upstream product

• 526190-09-0 2-(3,4-diethoxyphenyl)acetamide 
• 61381-04-2 2-(3,4-diethoxyphenyl)ethylamine 
• 38464-04-9 3,4-diethoxy-phenyl-acetic acid 
• 92157-09-0 methyl 2-(3,4-diethoxyphenyl)acetate 
• 69373-87-1 ethyl 2-(3,4-diethoxyphenyl)acetate 
• 1005009-95-9 2-(3,4-diethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 279262-08-7 3,4-diethoxyphenylboronic acid 
• 53207-08-2 4-bromo-1,2-diethoxybenzene 
• 17345-77-6 1-bromo-3,4-dihydroxybenzene 

Relevant articles and documents

Novel preparation method of drotaverine hydrochloride intermediate

The invention discloses a novel preparation method of a drotaverine hydrochloride intermediate. The preparation method comprises the steps that 1, 4-bromopyrocatechol serves as the raw material and issubjected to an ethylation reaction under the action of iodoethane or diethyl sulfate, and 1,2-diethoxy-4-bromobenzene is prepared; 2, 1,2-diethoxy-4-bromobenzene is subjected to a Suzuki-Miyaura coupling reaction and reacts with ethyl bromoacetate or methyl bromoacetate to prepare 3,4-diethoxyphenylaceticacid ester; 3, 3,4-diethoxyphenylaceticacid is hydrolyzed to prepare 3,4-diethoxyphenylaceticacid; 4, 3,4-diethoxyphenylaceticacid ester and ammonia are prepared into 3,4-diethoxyphenylacetamide; 5, 3,4-diethoxyphenylacetamide is reduced to prepare 3,4-diethoxyphenethylamine. The direct preparation method is used; in the process of preparing 3,4-diethoxyphenyl acetonitrile, application of sodium cyanide is avoided; when 3,4-diethoxyphenethylamine is prepared, lithium aluminium hydride isused for reduction, and a pressurized hydrogenation method is prevented from being used, so that the problems about safety and environment pollution are effectively solved, the process is simple andeasy to implement, and the practicality is high.