911050-87-8 Usage
Description
(S)-Methyl 4-(benzyloxycarbonylamino)-5-(tert-butyldimethylsilyloxy)pentanoate is a complex chiral ester derivative utilized in organic chemistry. It features a benzyloxycarbonylamino group and a tert-butyldimethylsilyloxy group, making it a valuable building block for synthesizing complex molecules, including pharmaceuticals and natural products. Its chiral nature is crucial for creating enantiopure compounds, which are significant in drug development and organic chemistry. The tert-butyldimethylsilyloxy group acts as a protective group, enabling selective reactions with other functional groups.
Uses
Used in Pharmaceutical Industry:
(S)-Methyl 4-(benzyloxycarbonylamino)-5-(tert-butyldimethylsilyloxy)pentanoate is used as a key intermediate for the synthesis of various pharmaceutical compounds. Its chiral nature allows for the creation of enantiopure compounds, which are essential in drug development due to their potential for improved efficacy and reduced side effects.
Used in Natural Product Synthesis:
In the field of natural product synthesis, (S)-Methyl 4-(benzyloxycarbonylamino)-5-(tert-butyldimethylsilyloxy)pentanoate is used as a building block for constructing complex natural products. Its structural features facilitate the development of novel compounds with potential biological activities.
Used in Organic Chemistry Research:
(S)-Methyl 4-(benzyloxycarbonylamino)-5-(tert-butyldimethylsilyloxy)pentanoate serves as an important intermediate in organic chemistry research, particularly in the development of new synthetic methods and the exploration of novel reaction mechanisms. Its versatility and the presence of protective groups make it a valuable tool for chemists working on complex molecular structures.
Check Digit Verification of cas no
The CAS Registry Mumber 911050-87-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,1,0,5 and 0 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 911050-87:
(8*9)+(7*1)+(6*1)+(5*0)+(4*5)+(3*0)+(2*8)+(1*7)=128
128 % 10 = 8
So 911050-87-8 is a valid CAS Registry Number.
InChI:InChI=1/C20H33NO5Si/c1-20(2,3)27(5,6)26-15-17(12-13-18(22)24-4)21-19(23)25-14-16-10-8-7-9-11-16/h7-11,17H,12-15H2,1-6H3,(H,21,23)
911050-87-8Relevant articles and documents
Design and synthesis of an orally active matrix metalloproteinase inhibitor
Yamamoto, Shingo,Nakatani, Shingo,Ikura, Masahiro,Sugiura, Tsuneyuki,Nishita, Yoshitaka,Itadani, Satoshi,Ogawa, Koji,Ohno, Hiroyuki,Takahashi, Kanji,Nakai, Hisao,Toda, Masaaki
, p. 6383 - 6403 (2007/10/03)
A series of 4-(4-phenoxy)benzoylamino-4-methoxymethyloxymethyl butyric acid hydroxamates, which were derived from l-glutamic acid, were synthesized and evaluated as matrix metalloproteinase inhibitors. Most of the compounds listed in Tables 1-3 exhibited
