91164-58-8 Usage
Description
3-methoxy PCP is an analog of PCP which binds the NMDA receptor (Ki = 20 nM) and serotonin transporter (Ki = 216 nM) with greater affinity than does PCP (Ki = 59 and 2,234 nM, respectively). The toxicological properties of this compound have not been reported. This product is intended for forensic and research purposes.
Uses
3-Methoxy
e but differs in terms binding affinity. 3-Methoxy
General Description
Also known as 3-Methoxyphencyclidine, 3-MeO-PCP is a dissociative hallucinogen and synthetic analog of PCP or phencyclidine. The designer drug first appeared in Europe in late 2012. This certified Snap-N-Spike? solution is suitable for use in PCP testing methods by LC/MS or GC/MS in clinical toxicology, urine drug testing, or forensic analysis applications.
Check Digit Verification of cas no
The CAS Registry Mumber 91164-58-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,1,1,6 and 4 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 91164-58:
(7*9)+(6*1)+(5*1)+(4*6)+(3*4)+(2*5)+(1*8)=128
128 % 10 = 8
So 91164-58-8 is a valid CAS Registry Number.
91164-58-8Relevant articles and documents
Synthesis and brain distribution of carbon-11 labeled analogs of antagonists for the NMDA receptor coupled PCP-binding site
Haradahira, Terushi,Sasaki, Sigeki,Maeda, Minoru,Kobayashi, Kaoru,Inoue, Osamu,Tomita, Urara,Nishikawa, Toru,Suzuki, Kazutoshi
, p. 843 - 858 (1998)
Two phencyclidine (PCP) analogs, 3 and 4, and one thienylcyclohexylpiperidine (TCP) analog, (±)6, were labeled with positron emitter carbon-11. These compounds displayed higher in vitro binding affinities than PCP itself for the PCP-binding site located inside the ion channel on the N-methyl-D-aspartate (NMDA) receptors. Brain distribution studies in mice showed different uptake characteristics between the PCP and TCP analogs, indicating their different in vivo interactions with the brain components including the PCP-binding site probably due to the different physicochemical properties of the molecules.
