912445-05-7 Usage
Description
ABT-888 is a potent, orally bioavailable PARP-1/-2 inhibitor that has been shown to potentiate DNA damaging agents. It is a promising pharmaceutical candidate for various applications in the field of oncology.
Uses
Used in Oncology:
ABT-888 is used as a potent PARP inhibitor for the treatment of cancer. It has been evaluated for its ability to potentiate temozolomide (TMZ) and develop a biological marker for PARP inhibition in vivo. This makes it a valuable tool in the development of targeted cancer therapies.
Used in Drug Development:
ABT-888 is used as a research tool in the development of new cancer treatments. Its potent PARP inhibition properties make it a valuable asset in the discovery and testing of novel therapeutic agents that can effectively target cancer cells and enhance the efficacy of existing treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 912445-05-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,2,4,4 and 5 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 912445-05:
(8*9)+(7*1)+(6*2)+(5*4)+(4*4)+(3*5)+(2*0)+(1*5)=147
147 % 10 = 7
So 912445-05-7 is a valid CAS Registry Number.
InChI:InChI=1/C13H16N4O.2ClH/c1-13(6-3-7-15-13)12-16-9-5-2-4-8(11(14)18)10(9)17-12;;/h2,4-5,15H,3,6-7H2,1H3,(H2,14,18)(H,16,17);2*1H/t13-;;/m1../s1
