91271-79-3

Basic information

• Product Name: 4-(PYRROLIDIN-1-YLMETHYL)BENZYLAMINE
• Synonyms: TIMTEC-BB SBB010837;4-(Pyrrolidin-1-ylmethyl)benzylamine 97%;1-[4-(pyrrolidin-1-ylmethyl)phenyl]methanamine(SALTDATA: FREE);BenzeneMethanaMine,4-(1-pyrrolidinylMethyl)-;4-pyrrolidin-1-MethylbenzylaMine;CHEMBRDG-BB 4011232;1-[4-(PYRROLIDIN-1-YLMETHYL)PHENYL]METHANAMINE;4-(PYRROLIDIN-1-YLMETHYL)BENZYLAMINE
• CAS NO: 91271-79-3
• Molecular Formula: C₁₂H₁₈N₂
• Molecular Weight: 190.28
• Mol File: 91271-79-3.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 120-125/0.5mm
• Flash Point: 120.8°C
• Appearance: /
• Density: 1.068g/cm³
• Vapor Pressure: 0.00144mmHg at 25°C
• Refractive Index: 1.584
• PKA: 9.80±0.20(Predicted)
• CAS DataBase Reference: 4-(PYRROLIDIN-1-YLMETHYL)BENZYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(PYRROLIDIN-1-YLMETHYL)BENZYLAMINE(91271-79-3)
• EPA Substance Registry System: 4-(PYRROLIDIN-1-YLMETHYL)BENZYLAMINE(91271-79-3)

Safety Data

• Hazard Codes: C
• HazardClass: IRRITANT
• Hazardous Substances Data: 91271-79-3(Hazardous Substances Data)

Usage

General Description

4-(pyrrolidin-1-ylmethyl)benzylamine, also known as PB-M1, is a chemical compound that belongs to the class of organic compounds known as phenylmethylamines. It is a psychoactive substance that acts as a selective serotonin reuptake inhibitor (SSRI), meaning it inhibits the reuptake of serotonin in the brain. 4-(PYRROLIDIN-1-YLMETHYL)BENZYLAMINE has been studied for its potential use in the treatment of various psychiatric and neurological disorders, including depression, anxiety, and obsessive-compulsive disorder. However, it also has potential for abuse and may produce psychoactive effects when consumed. Its precise mechanisms of action and potential therapeutic uses continue to be investigated.

InChI:InChI=1/C12H18N2/c13-9-11-3-5-12(6-4-11)10-14-7-1-2-8-14/h3-6H,1-2,7-10,13H2

Upstream product

• 105-07-7 4-cyanobenzaldehyde 
• 78064-96-7 4-(pyrrolidin-1-ylmethyl)benzonitrile 

Downstream Products

• 1272465-64-1 C₃₁H₄₅N₅O₇ 
• 1414782-04-9 N-(4-(pyrrolidin-1-ylmethyl)benzyl)-2-amino-4-nitrobenzamide 
• 1414782-03-8 7-nitro-3-(4-(pyrrolidin-1-ylmethyl)benzyl)quinazolin-4(3H)-one 
• 1414781-98-8 C₂₉H₂₆ClN₅O 
• 1414782-05-0 7-amino-3-(4-(pyrrolidin-1-ylmethyl)benzyl)quinazolin-4(3H)-one 

Relevant articles and documents

Mimicking the intramolecular hydrogen bond: Synthesis, biological evaluation, andmolecular modeling of benzoxazines and quinazolines as potential antimalarial agents

The intramolecular hydrogen bond formed between a protonated amine and a neighboring H-bond acceptor group in the side chain of amodiaquine and isoquine is thought to play an important role in their antimalarial activities. Here we describe isoquine-based

New carboxamide compounds having melanin concentrating hormone antagonistic activity, pharmaceutical preparations comprising these compounds and process for their manufacture

The present invention relates to carboxamide compounds of general formula I wherein the groups and residues A, B, W, X, Y, Z, R1, R2, R3 and k have the meanings given in claim 1. Moreover the invention relates to process for preparing the above mentioned carboxamides as well as pharmaceutical compositions containing at least one carboxamide according to the invention. In view of their MCH-receptor antagonistic activity the pharmaceutical compositions according to the invention are suitable for the treatment of metabolic disorders and/or eating disorders, particularly obesity, bulimia, anorexia, hyperphagia and diabetes.