91296-15-0 Usage
General Description
4-(2,6-diamino-9H-purin-9-yl)-2-(hydroxymethyl)cyclopentanol, also known as DPCP or diphenylcyclopropenone, is a chemical compound used in the treatment of alopecia areata, an autoimmune condition that causes hair loss. DPCP works by stimulating an allergic response in the skin, which in turn activates the immune system to target the affected area and promote hair regrowth. It is typically applied topically in a solution or cream form, and has been found to be effective in promoting hair regrowth in some individuals with alopecia areata. However, DPCP can cause side effects such as dermatitis and allergic reactions, and should be used under the guidance of a healthcare professional.
Check Digit Verification of cas no
The CAS Registry Mumber 91296-15-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,1,2,9 and 6 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 91296-15:
(7*9)+(6*1)+(5*2)+(4*9)+(3*6)+(2*1)+(1*5)=140
140 % 10 = 0
So 91296-15-0 is a valid CAS Registry Number.
91296-15-0Relevant articles and documents
Synthesis and Antiviral Activity of Carbocyclic Analogues of 2'-Deoxyribofuranosides of 2-Amino-6-substituted-purines and of 2-Amino-6-substituted-8-azapurines
Shealy, Y. Fulmer,O'Dell, C. Allen,Shannon, W. M.,Arnett, Gussie
, p. 1416 - 1421 (2007/10/02)
(+/-)-(1α,2β,4α)-4--2-hydroxycyclopentanemethanol (9) was synthesized by beginning with 2-amino-4,6-dichloropyrimidine and (+/-)-(1α,2β,4α)-4-amino-2-hydroxycyclopentanemethanol, preparing the 5- derivative of the resulting pyrimidine, and reducing the azo derivative.The carbocyclic analogue of 2-amino-6-chloropurine 2'-deoxyribofuranoside (10) was prepared from 9 and triethyl orthoformate, and the analogous 8-azapurine (11) was obtained by diazotizing 9.From 10 or 11, the carbocyclic analogues of 2'-deoxyguanosine, 2'-deoxythioguanosine, 2,6-diaminopurine 2'-deoxyribofuranoside, 2'-deoxy-8-azaguanosine, and 2,6-diamino-8-azapurine 2'-deoxyribofuranoside were prepared.All of these 2'-deoxyribofuranoside analogues were active against herpes simplex virus (types 1 and 2) replicating in cells in culture; some demonstrated potent activity.
