914458-27-8 Usage
General Description
JWH-369 is a synthetic cannabinoid that falls into the JWH series of compounds. It is a potent and selective agonist for the CB1 receptor, which is the same receptor that is targeted by THC, the active compound in marijuana. JWH-369 has been found to have psychoactive effects and is often used recreationally due to its ability to produce euphoria, relaxation, and altered perception. It is a highly potent chemical and has been shown to produce a range of physiological and psychological effects in users, and as with other synthetic cannabinoids, there is a risk of overdose and adverse reactions. Due to its potential for abuse, JWH-369 is categorized as a controlled substance in many jurisdictions.
Check Digit Verification of cas no
The CAS Registry Mumber 914458-27-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,4,4,5 and 8 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 914458-27:
(8*9)+(7*1)+(6*4)+(5*4)+(4*5)+(3*8)+(2*2)+(1*7)=178
178 % 10 = 8
So 914458-27-8 is a valid CAS Registry Number.
914458-27-8Relevant articles and documents
1-Alkyl-2-aryl-4-(1-naphthoyl)pyrroles: New high affinity ligands for the cannabinoid CB1 and CB2 receptors
Huffman, John W.,Padgett, Lea W.,Isherwood, Matthew L.,Wiley, Jenny L.,Martin, Billy R.
, p. 5432 - 5435 (2007/10/03)
Two series of 1-alkyl-2-aryl-4-(1-naphthoyl)pyrroles were synthesized and their affinities for the cannabinoid CB1 and CB2 receptors were determined. In the 2-phenyl series (5) the N-alkyl group was varied from n-propyl to n-heptyl. A second series of 23 1-pentyl-2-aryl-4-(1-naphthoyl)-pyrroles (6) was also prepared. Several compounds in both series have CB1 receptor affinities in the 6-30 nM range. The high affinities of these pyrrole derivatives relative to JWH-030 (1, R = C5H11) support the hypothesis that these pyrroles interact with the CB1 receptor primarily by aromatic stacking.
