916056-79-6

Basic information

• Product Name: ADX-102 (NS-2)
• Synonyms: ADX-102 (NS-2);Reproxalap
• CAS NO: 916056-79-6
• Molecular Formula: C12H13ClN2O
• Molecular Weight: 236.69742
• EINECS: -0
• Mol File: 916056-79-6.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: ADX-102 (NS-2)(CAS DataBase Reference)
• NIST Chemistry Reference: ADX-102 (NS-2)(916056-79-6)
• EPA Substance Registry System: ADX-102 (NS-2)(916056-79-6)

Safety Data

• Hazardous Substances Data: 916056-79-6(Hazardous Substances Data)

Usage

General Description

ADX-102, also known as NS-2, is a naturally occurring, non-prescription, non-steroidal, anti-inflammatory drug. It is a derivative of a naturally occurring compound and has demonstrated potent anti-inflammatory and analgesic effects. ADX-102 has shown promise in the treatment of inflammatory conditions, such as osteoarthritis and tendinitis, by reducing pain and inflammation. It is currently being developed as a topical gel for localized application and has the potential to offer a safe and effective alternative to traditional anti-inflammatory medications.

Upstream product

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• 1448228-06-5 1-(6-chloro-2-(ethoxycarbonyl)quinolin-3-yl)pyridin-1-ium bromide 

Downstream Products

• 1615680-56-2 2-(6-chloro-((3-((E)-2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-enyl)nona-2,4,6,8-tetraenylidene)amino)quinolin-2-yl)propan-2-ol 
• 1615680-58-4 C₃₂H₃₉ClN₂O 

Relevant articles and documents

ALDEHYDE CONJUGATES AND USES THEREOF

The present invention provides compounds and methods of use thereof for the treatment, prevention, and/or reduction of a risk of a disease, disorder, or condition in which aldehyde toxicity is implicated in the pathogenesis, including ocular disorders, skin disorders, conditions associated with injurious effects from blister agents, and autoimmune, inflammatory, neurological and cardiovascular diseases by the use of a primary amine to scavenge toxic aldehydes, such as MDA and HNE.

ALDEHYDE TRAPPING COMPOUNDS AND METHODS OF USE THEREOF

The present invention provides compounds and methods for the treatment, prevention, and/or reduction of a risk of a disease, disorder, or condition in which aldehyde toxicity is implicated in the pathogenesis, including ocular disorders, skin disorders, conditions associated with injurious effects from blister agents, and autoimmune, inflammatory, neurological and cardiovascular diseases by the use of a primary amine to scavenge toxic aldehydes, such as MDA and HNE.

DEUTERATED COMPOUNDS AND USES THEREOF

The present invention provides for the treatment, prevention, and/or reduction of a risk of a disease, disorder, or condition in which aldehyde toxicity is implicated in the pathogenesis, including ocular disorders, skin disorders, conditions associated with injurious effects from blister agents, and autoimmune, inflammatory, neurological and cardiovascular diseases by the use of a primary amine to scavenge toxic aldehydes, such as MDA and HNE.