91631-54-8

Basic information

• Product Name: Hydroxylamine-O-sulfonic acid, N-acetyl-N-(4-chlorophenyl)-, compd. with pyridine (1:1)
• CAS NO: 91631-54-8
• Molecular Formula: C8H8ClNO5S.C5H5N
• Molecular Weight: 344.776
• Mol File: 91631-54-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Hydroxylamine-O-sulfonic acid, N-acetyl-N-(4-chlorophenyl)-, compd. with pyridine (1:1)(CAS DataBase Reference)
• NIST Chemistry Reference: Hydroxylamine-O-sulfonic acid, N-acetyl-N-(4-chlorophenyl)-, compd. with pyridine (1:1)(91631-54-8)
• EPA Substance Registry System: Hydroxylamine-O-sulfonic acid, N-acetyl-N-(4-chlorophenyl)-, compd. with pyridine (1:1)(91631-54-8)

Safety Data

• Hazardous Substances Data: 91631-54-8(Hazardous Substances Data)

Upstream product

• 823-86-9 N-(4-chlorophenyl)hydroxylamine 
• 110-86-1 pyridine 
• 1503-91-9 N-(4-chlorophenyl)-N-hydroxyacetamide 

Downstream Products

• 103-90-2 4-acetaminophenol 
• 16323-09-4 N-(4-chloro-2-hydroxyphenyl)acetamide 
• 106-51-4 p-benzoquinone 
• 6975-29-7 N-(2,4-dichlorophenyl)acetamide 
• 3964-54-3 3-chloro-4-hydroxyacetanilide 
• 96648-97-4 2-sulfonoxy-4-chloroacetanilide 
• 539-03-7 N-(4-chlorophenyl)acetamide 
• 540-82-9 ethyl sulfate 
• 1503-91-9 N-(4-chlorophenyl)-N-hydroxyacetamide 

Relevant articles and documents

Solvolysis of N-Sulfonoxyacetanilides in Aqueous and Alcohol Solutions: Generation of Electrophilic Species

A series of ring-substituted N-sulfonoxyacetanilides (1a-f) were synthesized, and their solvolysis reactions in aqueous and alcohol solvents were studied.These compounds serve as models for the carcinogenic metabolites of polynuclear aromatic amides.Kinetic and product studies yielded evidence for solvolysis via N-O bond cleavage in aqueous solution with generation of tight ion pairs and solvent-separated ion pairs.The tight ion pairs, which cannot be trapped by nucleophiles or reducing agents, give rise to o-sulfonoxyacetanilides, while the solvent-separated ion pairs can be trapped by these reagents to yield ring-substituted compounds and reduction products.The para-substituted N-sulfonoxyacetanilides yield substantial amounts of highly electrophilic p-benzoquinone imine derivatives such as 10 during solvolysis in aqueous media.In ethanol these esters solvolyze exclusively via S-O bond cleavage with apparent production of SO3.This study demonstrates that electrophilic species other than nitrenium ions can be generated during the solvolysis of N-sulfonoxy-N-arylamides.These species may play a role in the in vivo activity of these metabolites.