916458-79-2

Basic information

• Product Name: 2-(4-benzyloxyphenyl)ethyl-(2,3,4,6-tetra-O-acetyl)-β-D-glucopyranoside
• Synonyms: 2-(4-benzyloxyphenyl)ethyl-(2,3,4,6-tetra-O-acetyl)-β-D-glucopyranoside
• CAS NO: 916458-79-2
• Molecular Weight: 558.582
• Mol File: 916458-79-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-(4-benzyloxyphenyl)ethyl-(2,3,4,6-tetra-O-acetyl)-β-D-glucopyranoside(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-benzyloxyphenyl)ethyl-(2,3,4,6-tetra-O-acetyl)-β-D-glucopyranoside(916458-79-2)
• EPA Substance Registry System: 2-(4-benzyloxyphenyl)ethyl-(2,3,4,6-tetra-O-acetyl)-β-D-glucopyranoside(916458-79-2)

Safety Data

• Hazardous Substances Data: 916458-79-2(Hazardous Substances Data)

Upstream product

• 83-87-4 D-glucose pentaacetate 
• 61439-59-6 2-(4-benzyloxyphenyl)ethanol 
• 74808-10-9 O-(2,3,4,6-Tetra-O-acetyl-α-D-glucopyranosyl)trichloroacetimidate 
• 6919-96-6 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide 
• 58609-13-5 4-(benzyloxy)phenylacetic acid benzyl ester 
• 156-38-7 4-hydroxyphenylacetate 
• 3947-62-4 2,3,4,5-tetra-O-acetyl-D-glucopyranose 

Downstream Products

• 10338-51-9 Salidroside 
• 916458-88-3 (4-benzyloxyphenyl)ethyl (2,3,4-tri-O-acetyl-α-L-rhamnopyranosyl)-(1->3)-2-O-acetyl-4-O-[(E)-3,4-di-O-benzyl]caffeoyl-6-O-tert-butyldimethylsilyl-β-D-glucopyranoside 
• 916458-87-2 (4-benzyloxyphenyl)ethyl (2,3,4-tri-O-acetyl-α-L-rhamnopyranosyl)-(1->3)-2-O-acetyl-6-O-tert-butyldimethylsilyl-β-D-glucopyranoside 
• 916458-86-1 (4-benzyloxyphenyl)ethyl (2,3,4-tri-O-acetyl-α-L-rhamnopyranosyl)-(1->3)-2-O-acetyl-β-D-glucopyranoside 
• 110978-95-5 2-(4-hydroxyphenyl)ethyl 6-O-(E)-(3-methoxy-4-hydroxy)cinnamoyl β-D-glucopyranoside 
• 955944-30-6 2-(4-benzyloxyphenyl)ethyl 2,3-di-O-benzyl-4-O-[(E)-4-O-benzylferuloyl]-β-D-glucopyranoside 
• 955944-29-3 2-(4-benzyloxyphenyl)ethyl 2,3-di-O-benzyl-6-O-[(E)-4-O-benzylferuloyl]-β-D-glucopyranoside 
• 955944-28-2 2-(4-benzyloxyphenyl)ethyl 2,3-di-O-benzyl-β-D-glucopyranoside 
• 110344-59-7 2-(4-hydroxyphenyl)ethyl 4-Ο-(E)-Feruloyl-β-D-glucopyranoside 
• 183209-56-5 2-(4-benzyloxyphenyl)ethyl β-D-glucopyranoside 

Relevant articles and documents

Total synthesis of phenylpropanoid glycosides, grayanoside A and syringalide B, through a common intermediate

Phenylpropanoid glycosides are known as bioactive natural products. Two of them, grayanoside A (1) and syringalide B (2), were synthesized through a common intermediate, using benzyl as temporary protecting group following a shorter route.

Synthesis, biological activity of salidroside and its analogues

Salidroside is a phenylpropanoid glycoside isolated from Rhodiola rosea L., a traditional Chinese medicinal plant, and has displayed a broad spectrum of pharmacological properties. In this paper, about 18 novel salidroside analogues were prepared through Koenigs-Knorr method, the effects of these compounds over PC12 was assessed with the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) method. The novel compounds differ in the substituents attached to the benzene ring or in the glycosyl donor. According to the data, compounds (3,5-dimethoxyphenyl)methyl β-D-glucopyranoside and (3,5-dimethoxyphenyl) methyl β-D-galactopyranoside with methoxy group at 3 and 5-positions of the benzene ring were the most viability at concentration of 300 μmol/l and 60 μmol/l, respectively.