916488-42-1 Usage
General Description
1-(2-Methanesulfonyl-phenyl)-piperazine dihydrochloride is a chemical compound that belongs to the class of piperazine derivatives. It is a dihydrochloride salt of the piperazine compound, which is commonly used in the synthesis of pharmaceuticals and drugs. 1-(2-METHANESULFONYL-PHENYL)-PIPERAZINE DIHYDROCHLORIDE has a piperazine ring with a methanesulfonyl-phenyl substituent at the 1 position, and it is present in the form of a dihydrochloride salt, which makes it more stable and suitable for pharmaceutical applications. The chemical may have various pharmacological properties and may be used in the treatment of certain medical conditions, but its specific uses and effects would depend on the context and formulation in which it is utilized.
Check Digit Verification of cas no
The CAS Registry Mumber 916488-42-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,6,4,8 and 8 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 916488-42:
(8*9)+(7*1)+(6*6)+(5*4)+(4*8)+(3*8)+(2*4)+(1*2)=201
201 % 10 = 1
So 916488-42-1 is a valid CAS Registry Number.
InChI:InChI=1/C11H16N2O2S.ClH/c1-16(14,15)11-5-3-2-4-10(11)13-8-6-12-7-9-13;/h2-5,12H,6-9H2,1H3;1H
916488-42-1Relevant articles and documents
Novel potent neuropeptide Y Y5 receptor antagonists: Synthesis and structure-activity relationships of phenylpiperazine derivatives
Takahashi, Toshiyuki,Sakuraba, Aya,Hirohashi, Tomoko,Shibata, Takunobu,Hirose, Masaaki,Haga, Yuji,Nonoshita, Katsumasa,Kanno, Tetsuya,Ito, Junko,Iwaasa, Hisashi,Kanatani, Akio,Fukami, Takehiro,Sato, Nagaaki
, p. 7501 - 7511 (2007/10/03)
A series of phenylpiperazine derivatives were synthesized and evaluated for their neuropeptide Y (NPY) Y5 receptor antagonistic activities. The benzindane portion of 2 was replaced by 1-phenylpiperazine, resulting in novel urea derivative 3f. Subsequent optimization of the phenylpiperazine template by substitution of the phenyl moiety resulted in a series of (2-methanesulfonamidephenyl)piperazine derivatives that showed potent binding affinity and antagonistic activity for the Y5 receptor.
