916908-83-3

Basic information

• Product Name: 3-(2-aminophenyl)-3-hydroxy-2-methylpropanenitrile
• Synonyms: 3-(2-aminophenyl)-3-hydroxy-2-methylpropanenitrile
• CAS NO: 916908-83-3
• Molecular Weight: 176.218
• Mol File: 916908-83-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(2-aminophenyl)-3-hydroxy-2-methylpropanenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-aminophenyl)-3-hydroxy-2-methylpropanenitrile(916908-83-3)
• EPA Substance Registry System: 3-(2-aminophenyl)-3-hydroxy-2-methylpropanenitrile(916908-83-3)

Safety Data

• Hazardous Substances Data: 916908-83-3(Hazardous Substances Data)

Upstream product

• 225237-20-7 2-(hydroxy(2-nitrophenyl)methyl)acrylonitrile 

Relevant articles and documents

The Baylis-Hillman approach to quinoline derivatives

Baylis-Hillman reactions of 2-nitrobenzaldehydes with various activated alkenes afford adducts that undergo reductive cyclisation to quinoline derivatives. The chemo- and regioselectivity of cyclisation appears to be influenced by the choice of both the substrate and the reagent system, and competing reactions have been observed. The Royal Society of Chemistry 2006.