917-72-6Relevant articles and documents
SPECTROSCOPIC STUDY OF HYDROGEN BONDS IN DIMETHYLAMINE AND ITS DEUTERO ANALOGS IN THE TEMPERATURE RANGE OF 4-300 K
Pesterev, V. I.,Agashkin, O. V.
, p. 841 - 844 (1988)
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Deuterated arglabin dimethylamine fumarate and preparation method thereof, and application of deuterated dimethylamine fumarate to drug preparation
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Paragraph 0005, (2018/07/30)
The invention relates to deuterated arglabin dimethylamine fumarate with a structure as shown in a formula (I) which is described in the specification and a preparation method thereof, and applicationof deuterated arglabin dimethylamine fumarate to drug preparation.
Thermolysis, Photolysis, and Acid Catalysis of an α-(Dimethylamino)azoalkane. Amino Stabilization of a Carbon Radical Center
Engel, Paul S.,Wu, Wen-Xue
, p. 2720 - 2725 (2007/10/02)
The unsymmetrical azoalkane 2-(tert-butylazo)-2-(dimethylamino)propane (7) has been synthesized cleanly by nucleophilic displacement of chloride from the corresponding α-chloroazoalkane 5 with dimethylamine.Thermolysis of 7 in hydrocarbon solvents affords typical radical-derived products and exhibits activation parameters ΔH(excit.) = 26.6 +/- 0.4 kcal/mol and ΔS(excit.) = -6.6 +/- 1.1 eu.Since the thermolysis rate of 7 is 104 faster than that of 1,2-di-tert-butyldiazene, the large stabilization of α-amino radicals is supported.Unusual products were obtained in acetonitrile, suggesting reduction of the azo linkage by 2-(dimethylamino)-2-propyl radicals and cleavage of the resulting hydrazyl radicals.In protic solvents, 7 undergoes acid catalyzed decomposition via tert-butyldiazene as a postulated intermediate.