917807-93-3

Basic information

• Product Name: 2-Thiazolamine, 4-(3-chlorophenyl)-5-(2-fluoro-4-pyridinyl)-N-methyl-
• CAS NO: 917807-93-3
• Molecular Formula: C15H11ClFN3S
• Molecular Weight: 319.79
• Mol File: 917807-93-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Thiazolamine, 4-(3-chlorophenyl)-5-(2-fluoro-4-pyridinyl)-N-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Thiazolamine, 4-(3-chlorophenyl)-5-(2-fluoro-4-pyridinyl)-N-methyl-(917807-93-3)
• EPA Substance Registry System: 2-Thiazolamine, 4-(3-chlorophenyl)-5-(2-fluoro-4-pyridinyl)-N-methyl-(917807-93-3)

Safety Data

• Hazardous Substances Data: 917807-93-3(Hazardous Substances Data)

Upstream product

• 760936-81-0 2-bromo-1-(3-chlorophenyl)-2-(2-fluoro-4-pyridyl) ethanone 
• 598-52-7 1-(methyl)-thiourea 

Relevant articles and documents

NEW SUBSTITUTED 1,3-THIAZOLE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF HAVING IMMUNOSUPPRESSION AND INFLAMMATION INHIBITORY ACITIVITY, INTERMEDIATE COMPOUNDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, A PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME

Disclosed relates to new substituted 1,3-thiazole derivatives or pharmaceutically acceptable salts thereof having immunosuppresion and inflammation inhibitory activity, intermediate compounds or pharmaceutically acceptable salts thereof, a process for the preparation thereof, and a pharmaceutical composition comprising the same. The compound of the present invention having excellent TNF-α inhibitory activity and inflammation inhibitory activity can be effectively used in the prevention and treatment of TNF-α related diseases.