918344-20-4Relevant articles and documents
NOVEL PROCESS FOR PREPARATION OF O-DESMETHYLVENLAFAXINE
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Page/Page column 7; 19, (2009/08/14)
The present invention relates to the novel processes for the preparation of 4-(2- (dimethylamino)-1-(1-hydroxycyclohexyl)ethyl)phenol, commonly known as O- desmethylvenlafaxine of formula (I) and its pharmaceutically acceptable salts thereof The present invention also relates to the novel process for the preparation of O- desmethylvenlafaxine of formula (I) and its pharmaceutically acceptable salts thereof formula (V) or formula (VI) formula (I) or formula (VII) wherein, R is hydrogen, methoxyethoxymethyl (MEM), methoxymethyl (MOM), aryloyl, arylsulfonyl, tetrahydropyranyl or substituted silyl.
PROCESS FOR THE PREPARATION OF 1-[CYANO (4-HYDROXYPHENYL)METHYL]CYCLOHEXANOL COMPOUNDS
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Page/Page column 6-7, (2008/06/13)
Process for the preparation of 1-[cyano (phenyl) methyl] cyclohexanol compounds of general formula (I) in which R1 is hydrogen, (C1-4) alkyl or (C1-4) alkoxy, wherein a compound of general formula (II) in which R1/su