918898-03-0

Basic information

• Product Name: 4-aMino-2,6-dichloronicotinaMide
• Synonyms: 4-aMino-2,6-dichloronicotinaMide
• CAS NO: 918898-03-0
• Molecular Formula: C₆H₅Cl₂N₃O
• Molecular Weight: 206.0294
• Mol File: 918898-03-0.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-aMino-2,6-dichloronicotinaMide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-aMino-2,6-dichloronicotinaMide(918898-03-0)
• EPA Substance Registry System: 4-aMino-2,6-dichloronicotinaMide(918898-03-0)

Safety Data

• Hazardous Substances Data: 918898-03-0(Hazardous Substances Data)

Usage

Description

4-Amino-2,6-dichloronicotinamide is a white to off-white crystalline powder that belongs to the class of nicotinamide derivatives. It has a molecular formula of C6H5Cl2N3O and is characterized by its unique chemical properties and potential biological activities.

Uses

Used in Pharmaceutical Synthesis:
4-Amino-2,6-dichloronicotinamide is used as a key intermediate in the synthesis of various pharmaceuticals. Its unique chemical properties make it a valuable building block for the development of new drugs and bioactive compounds.
Used in Agrochemical Production:
4-aMino-2,6-dichloronicotinaMide is also utilized in the production of agrochemicals, contributing to the development of effective and innovative solutions for agriculture.
Used in Organic Intermediates:
4-Amino-2,6-dichloronicotinamide serves as an essential organic intermediate in the synthesis of a wide range of chemicals, further expanding its applications across various industries.
Used in Medicine:
Due to its potential biological activities, 4-Amino-2,6-dichloronicotinamide has potential applications in the field of medicine, where it can be used to develop new therapeutic agents and treatments.
Used in Material Science:
4-aMino-2,6-dichloronicotinaMide's unique properties also make it a promising candidate for applications in material science, where it can contribute to the development of new materials with specific properties and functions.

Upstream product

• 5398-44-7 2,6-dichloropyridine-4-carboxylic acid 

Downstream Products

• 1391001-04-9 7-(2,6-dichlorobenzyl)-5-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}pyrido[4,3-d]pyrimidin-4(3H)-one 
• 1390656-45-7 5-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino)-7-chloropyrido[4,3-d]pyrimidin-4(3H)-one 
• 1390655-11-4 7-(2,6-dichlorobenzyl)-5-{[2-methoxy-4-(piperazin-1-yl)phenyl]amino}-2,3-dihydropyrido[4,3-d]pyrimidin-4(1H)-one 
• 1390656-47-9 tert-butyl 4-(4-(7-(2,6-dichlorobenzyl)-1,2,3,4-tetrahydro-4-oxopyrido[4,3-d]pyrimidin-5-ylamino)-3-methoxyphenyl)piperazine-1-carboxylate 
• 1390656-46-8 tert-butyl 4-(4-(7-(2,6-dichlorobenzyl)-3,4-dihydro-4-oxopyrido[4,3-d]pyrimidin-5-ylamino)-3-methoxyphenyl)piperazine-1-carboxylate 
• 1391001-24-3 tert-butyl 4-(4-(7-chloro-3,4-dihydro-4-oxopyrido[4,3-d]pyrimidin-5-ylamino)-3-methoxyphenyl)piperazine-1-carboxylate 
• 918898-07-4 7-chloro-4-ethoxy-2-methyl-5-phenyl-pyrido[4,3-d]pyrimidine 
• 1263075-67-7 5-(2-(1H-pyrazol-4-yl)ethoxy)-3-methyl-7-(4-morpholinophenyl)pyrido[4,3-d]pyrimidin-4(3H)-one 
• 1263075-52-0 5-(5-(hydroxymethyl)thiophen-2-yl)-3-methyl-7-(4-morpholinophenyl)pyrido[4,3-d]pyrimidin-4(3H)-one 
• 1263077-37-7 5-chloro-3-methyl-7-(4-morpholinophenyl)pyrido[4,3-d]pyrimidin-4(3H)-one 
• 1263077-36-6 5-(4-methoxybenzyloxy)-3-methyl-7-(4-morpholinophenyl)pyrido[4,3-d]pyrimidin-4(3H)-one 
• 1263077-35-5 7-chloro-5-(4-methoxybenzyloxy)-3-methylpyrido[4,3-d]pyrimidin-4(3H)-one 
• 1263074-53-8 (R)-7-(4-(4-isopropylpiperazin-1-yl)phenyl)-3-methyl-5-(tetrahydrofuran-3-ylamino)pyrido[4,3-d]pyrimidin-4(3H)-one 
• 1263075-34-8 3-methyl-5,7-bis(4-morpholinophenyl)pyrido[4,3-d]pyrimidin-4(3H)-one 

Relevant articles and documents

BICYCLIC INHIBITORS OF ALK

The present invention relates to compounds of formula (1) or pharmaceutical acceptable salts, Formula (1) wherein R1, R2, R3, X, Y, Z, A, B, G1, m, and n are defined in the description. The present invention relates also to compositions containing said compounds which are useful for inhibiting kinases such as ALK and methods of treating diseases such as cancer.

BICYCLIC INHIBITORS OF ANAPHASTIC LYMPHOMA KINASE

Disclosed are compounds of formula (Ⅰ) and their pharmaceutical acceptable salts, wherein R1, R2, R3, X, Y, Z, A, B, G1, m and n are defined in the description. The compositions containing the said compounds used for inhibiting kinases such as anaphastic lymphoma kinase (ALK) and methods of treating diseases such as cancer are disclosed.