919119-62-3

Basic information

• Product Name: 1H-INDOLE-2-CARBOXYLIC ACID, 7-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-, ETHYL ESTER
• Synonyms: 1H-INDOLE-2-CARBOXYLIC ACID, 7-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-, ETHYL ESTER;ethyl 7-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-2-carboxylate
• CAS NO: 919119-62-3
• Molecular Formula: C₁₇H₂₂BNO₄
• Molecular Weight: 0
• Mol File: 919119-62-3.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1H-INDOLE-2-CARBOXYLIC ACID, 7-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-, ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-INDOLE-2-CARBOXYLIC ACID, 7-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-, ETHYL ESTER(919119-62-3)
• EPA Substance Registry System: 1H-INDOLE-2-CARBOXYLIC ACID, 7-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-, ETHYL ESTER(919119-62-3)

Safety Data

• Hazardous Substances Data: 919119-62-3(Hazardous Substances Data)

Usage

General Description

1H-Indole-2-carboxylic acid, 7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, ethyl ester is a chemical compound with potential use in medicinal chemistry and organic synthesis. It is a derivative of indole-2-carboxylic acid, which is a heterocyclic compound with various pharmaceutical and biological activities. The ethyl ester group in this compound makes it more soluble and stable, and the boron-containing group can be useful for various chemical reactions. 1H-INDOLE-2-CARBOXYLIC ACID, 7-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-, ETHYL ESTER has the potential to be used in the development of new pharmaceuticals, agrochemicals, and materials. Its specific properties and potential applications make it a valuable tool in chemical research and development.

Upstream product

• 3770-50-1 2-carbethoxyindole 
• 25015-63-8 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane 
• 16732-69-7 ethyl 7-bromo-1H-indole-2-carboxylate 
• 73183-34-3 bis(pinacol)diborane 

Downstream Products

• 154422-25-0 ethyl 7-phenyl-1H-indole-2-carboxylate 

Relevant articles and documents

TRANSGLUTAMINASE 2 (TG2) INHIBITORS

Described herein are compounds and pharmaceutical compositions containing such compounds which inhibit transglutaminase 2 (TG2). Also described herein are methods for using such TG2 inhibitors, alone or in combination with other compounds, for treating diseases or conditions that would benefit from TG2 inhibition.

A highly selective Ir-catalyzed borylation of 2-substituted indoles: a new access to 2,7- and 2,4,7-substituted indoles

The selective CH-functionalization of 2-substituted indoles is presented. Using bis(pinacolato)diboron (2) in the presence of iridium complexes, a novel catalytic mono-borylation is observed preferentially at the 7-position of the indole. This allows for