919284-91-6Relevant articles and documents
Synthesis and SAR of GlyT1 inhibitors derived from a series of N-((4-(morpholine-4-carbonyl)-1-(propylsulfonyl)piperidin-4-yl)methyl)benzamides
Zhao, Zhijian,O'Brien, Julie A.,Lemaire, Wei,Williams Jr., David L.,Jacobson, Marlene A.,Sur, Cyrille,Pettibone, Doug J.,Tiller, Philip R.,Smith, Sheri,Hartman, George D.,Wolkenberg, Scott E.,Lindsley, Craig W.
, p. 5968 - 5972 (2007/10/03)
This Letter describes the synthesis and SAR, developed through an iterative analog library approach, of potent and selective non-sarcosine-derived GlyT1 inhibitors.