92-18-2

Basic information

• Product Name: N,N-diethyl-m-anisidine
• Synonyms: N,N-diethyl-m-anisidine;N,N-diethyl-3-methoxybenzenamine;3-Methoxy-N,N-diethylbenzenamine;N,N-Diethyl-3-methoxyaniline;diethyl-(3-methoxyphenyl)amine;N,N-diethyl-N-(3-methoxyphenyl)amine;BenzenaMine, N,N-diethyl-3-Methoxy-
• CAS NO: 92-18-2
• Molecular Formula: C₁₁H₁₇NO
• Molecular Weight: 179.25878
• EINECS: 202-134-7
• Mol File: 92-18-2.mol
• Article Data: 23

Chemical Properties

• Boiling Point: 251.132°C at 760 mmHg
• Flash Point: 73.332°C
• Appearance: /
• Density: 0.972g/cm³
• Vapor Pressure: 0.021mmHg at 25°C
• Refractive Index: 1.525
• CAS DataBase Reference: N,N-diethyl-m-anisidine(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-diethyl-m-anisidine(92-18-2)
• EPA Substance Registry System: N,N-diethyl-m-anisidine(92-18-2)

Safety Data

• Hazardous Substances Data: 92-18-2(Hazardous Substances Data)

Usage

General Description

N,N-diethyl-m-anisidine is an organic compound that is commonly used as an intermediate in the production of dyes and pigments. It is a yellow to brown solid with a strong amine-like odor, and it is insoluble in water but soluble in organic solvents. This chemical is considered to be harmful if swallowed, inhaled, or absorbed through the skin, and may cause irritation to the respiratory system and skin. Additionally, it has been classified as a potential carcinogen and mutagen, and therefore should be handled with caution. Overall, N,N-diethyl-m-anisidine is a widely used chemical in various industrial applications, but its potential health hazards warrant careful handling and proper safety precautions.

InChI:InChI=1/C11H17NO/c1-4-12(5-2)10-7-6-8-11(9-10)13-3/h6-9H,4-5H2,1-3H3

Upstream product

• 104-92-7 1-bromo-4-methoxy-benzene 
• 60-29-7 diethyl ether 
• 816-43-3 lithium diethylamide 
• 321-28-8 1-fluoro-2-methoxybenzene 
• 529-28-2 4-iodoanisol 
• 766-51-8 2-Chloroanisole 
• 2845-89-8 1-chloro-3-methoxy-benzene 
• 77-78-1 dimethyl sulfate 
• 91-68-9 3-diethylaminophenol 
• 2398-37-0 3-methoxyphenyl bromide 
• 1066-87-1 (N,N-diethylamino)tributyltin 
• 117-80-6 2,3-Dichloro-1,4-naphthoquinone 
• 91-66-7 N,N-diethylaniline 
• 536-90-3 m-Anisidine 

Downstream Products

• 89787-46-2 2-[2-(4-Diethylamino-2-methoxy-phenylazo)-benzothiazol-6-yloxy]-ethanol 
• 1061330-81-1 C₁₉H₂₃NO₂ 
• 1061330-78-6 C₁₉H₂₃NO₂ 
• 1061330-79-7 C₁₉H₂₃NO₂ 
• 59404-96-5 4-diethylamino-2-methoxy-2'-carboxybenzophenone 
• 1309568-64-6 2-[4-(diethylamino)-2-methoxyphenyl]ethene-1,1,2-tricarbonitrile 
• 302776-72-3 (4-(diethylamino)-2-hydroxyphenyl)(phenyl)methanone 
• 304682-92-6 1-(4-((4-(diethylamino)-2-methoxyphenyl)diazenyl)phenyl)ethanone 
• 1380544-23-9 4,4'-methylenebis(N,N-diethyl-3-methoxyaniline) 
• 5809-23-4 2'-Carboxy-4-diethylamino-2-hydroxybenzophenon 
• 1034886-73-1 C₂₈H₃₄N₃O₂⁽¹⁺⁾*Cl^(1-) 
• 89787-63-3 C₂₁H₂₇N₄O₃S⁽¹⁺⁾*CH₃O₄S^(1-) 
• 105810-39-7 C₂₆H₃₂N₂O₄ 
• 91274-29-2 3-(2-acetoxy-4-diethylamino-phenyl)-3-(4-diethylamino-2-methoxy-phenyl)-phthalide 

Relevant articles and documents

OXAZINE-BASED FLUOROPHORE COMPOUNDS FOR NERVE-SPECIFIC IMAGING

This invention concerns novel oxazine-based fluorophore compounds useful in invivo nerve imaging, as well as compositions comprising them and methods for their use.

NEAR-INFRARED NERVE-SPARING FLUOROPHORES

Provided are far red to near-infrared nerve-sparing fluorescent compounds, compositions comprising them, and methods of their use in medical procedures.

Visible-Light-Enabled Direct Decarboxylative N-Alkylation

The development of efficient and selective C?N bond-forming reactions from abundant feedstock chemicals remains a central theme in organic chemistry owing to the key roles of amines in synthesis, drug discovery, and materials science. Herein, we present a dual catalytic system for the N-alkylation of diverse aromatic carbocyclic and heterocyclic amines directly with carboxylic acids, by-passing their preactivation as redox-active esters. The reaction, which is enabled by visible-light-driven, acridine-catalyzed decarboxylation, provides access to N-alkylated secondary and tertiary anilines and N-heterocycles. Additional examples, including double alkylation, the installation of metabolically robust deuterated methyl groups, and tandem ring formation, further demonstrate the potential of the direct decarboxylative alkylation (DDA) reaction.