92-47-7

Basic information

• Product Name: 3,4-dihydro-6-methyl-2H-1-benzopyran-2-one
• Synonyms: 3,4-dihydro-6-methyl-2H-1-benzopyran-2-one;6-Methyl-3,4-dihydro-2H-1-benzopyran-2-one
• CAS NO: 92-47-7
• Molecular Formula: C₁₀H₁₀O₂
• Molecular Weight: 162.1852
• EINECS: 202-157-2
• Mol File: 92-47-7.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 288.4°C at 760 mmHg
• Flash Point: 116.5°C
• Appearance: /
• Density: 1.157g/cm³
• Vapor Pressure: 0.00234mmHg at 25°C
• Refractive Index: 1.555
• CAS DataBase Reference: 3,4-dihydro-6-methyl-2H-1-benzopyran-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-dihydro-6-methyl-2H-1-benzopyran-2-one(92-47-7)
• EPA Substance Registry System: 3,4-dihydro-6-methyl-2H-1-benzopyran-2-one(92-47-7)

Safety Data

• Hazardous Substances Data: 92-47-7(Hazardous Substances Data)

Usage

Synthesis Reference(s)

The Journal of Organic Chemistry, 29, p. 2971, 1964 DOI: 10.1021/jo01033a040

InChI:InChI=1/C10H10O2/c1-7-2-4-9-8(6-7)3-5-10(11)12-9/h2,4,6H,3,5H2,1H3

Upstream product

• 3751-48-2 3-(3-methylphenyl)propanoic acid 
• 1119700-53-6 2-hydroxy-5-methylcinnamaldehyde 
• 85960-67-4 (±)-6-methylchroman-2-ol 
• 288310-94-1 1,1,1-trifluoro-4-(4-methylphenyl)butan-2-one 
• 25173-37-9 3-(4-methylphenoxy)propionic acid 
• 71-43-2 benzene 
• 7664-93-9 sulfuric acid 
• 106-44-5 p-cresol 
• 140-88-5 ethyl acrylate 
• 87823-56-1 methyl-6 diethoxy-2,2 benzopyranne-1 
• 92-48-8 6-methylcoumarin 
• 542-76-7 3-Chloropropionitrile 

Downstream Products

• 783333-05-1 3-(2-((tert-butyldimethylsilyl)oxy)-5-methylphenyl)propan-1-ol 
• 1360546-17-3 (E)-ethyl 3-(2-(3-(dibenzylamino)-3-thioxopropyl)-4-methylphenyl)acrylate 
• 1360546-27-5 ethyl 2-((1S,2R)-2-(dibenzylcarbamothioyl)-5-methyl-2,3-dihydro-1H-inden-1-yl)acetate 
• 1261034-13-2 C₁₈H₃₁NO₃SSi 
• 1261034-11-0 C₁₇H₃₁NO₃SSi 
• 1261034-10-9 C₁₆H₂₇NO₂Si 
• 1221740-98-2 N-(3-(2-(tert-butyldimethylsilyloxy)phenyl)propyl)ethene sulfonamide 
• 1261034-15-4 C₁₂H₁₇NO₃S 
• 1221741-00-9 N-(3-(2-hydroxyphenyl)propyl)ethenesulfonamide 
• 1261034-03-0 C₁₁H₁₇NO₃S 
• 952568-48-8 (R)-tert-butyl 3-benzyl-4-(3-(2-hydroxy-5-methylphenyl)propanoyl)piperazine-1-carboxylate 
• 22242-84-8 4-hydroxy-7-methyl-1-indanone 

Relevant articles and documents

Facile conversion of lactols to lactones using IBX

Lactols, which are insoluble or only sparingly soluble in most of the organic solvents that are generally employed for oxidation, are converted to lactones using o-iodoxybenzoic acid (IBX) in a facile manner under modified experimental conditions [EtOAc-DMSO (9:1) mixture at reflux] in good to excellent isolated yields (66-91%).

Hydrolase-mediated resolution of the hemiacetal in 2-chromanols: The impact of remote substitution

Hydrolase-catalysed dynamic kinetic resolutions of chroman-2-ol and 3-methyl chroman-2-ol can be effected with up to 88% conversion and 92% ee through the use of organic solvents. Extension to the resolution of the tolterodine precursor 1 proved more challenging. The presence of the remote phenyl substituent had a significant impact on the resolution and it was not possible to achieve high enantioselectivity together with efficient conversion from the focussed panel of enzymes screened.

SYNTHETIC METHODS

New strategies for the synthesis of salicylaldehyde derivatives having utility production of catalytic metal complexes.