92-65-9

Basic information

• Product Name: 2-(4-amino-N-ethylanilino)ethanol
• Synonyms: 2-(4-amino-N-ethylanilino)ethanol;4-Amino-N-Ethyl-N-Hydroxyethyl Aniline Sulfate;N-Ethyl-N-2-Hydroxyethyl-P-Phenylenediamine;N-Ethyl-N-(2-hydroxyethyl)-p-phenylenediamine (base and/or unspecified salt;2-[N-(4-Aminophenyl)-N-ethylamino]ethanol;4-Amino-N-ethyl-N-(2-hydroxyethyl)aniline;4-Amino-N-ethyl-N-(β-hydroxyethyl)aniline;N-Ethyl-N-(2-hydroxyethyl)-1,4-phenylenediamine
• CAS NO: 92-65-9
• Molecular Formula: C₁₀H₁₆N₂O
• Molecular Weight: 278.32532
• EINECS: 202-175-0
• Product Categories: Intermediates of Dyes and Pigments
• Mol File: 92-65-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 344.7°C at 760 mmHg
• Flash Point: 162.3°C
• Appearance: /
• Density: 1.124g/cm³
• Vapor Pressure: 2.46E-05mmHg at 25°C
• Refractive Index: 1.61
• CAS DataBase Reference: 2-(4-amino-N-ethylanilino)ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-amino-N-ethylanilino)ethanol(92-65-9)
• EPA Substance Registry System: 2-(4-amino-N-ethylanilino)ethanol(92-65-9)

Safety Data

• Hazardous Substances Data: 92-65-9(Hazardous Substances Data)

Usage

General Description

2-(4-amino-N-ethylanilino)ethanol is a chemical compound with the molecular formula C10H16N2O. It is an ethanolamine derivative containing an aniline group and an ethylamine group. 2-(4-amino-N-ethylanilino)ethanol is commonly used as an intermediate in the synthesis of pharmaceuticals, dyes, and other organic compounds. It has potential applications in the production of anti-inflammatory drugs and antibiotics. The chemical properties and reactivity of 2-(4-amino-N-ethylanilino)ethanol make it a valuable building block in organic chemistry, allowing for the creation of more complex molecules through various chemical reactions.

InChI:InChI=1/C10H16N2O/c1-2-12(7-8-13)10-5-3-9(11)4-6-10/h3-6,13H,2,7-8,11H2,1H3

Upstream product

• 92-50-2 2-( N-ethylanilino)ethanol 

Relevant articles and documents

Hypersensitive azobenzenes: Facile synthesis of clickable and cleavable azo linkers with tunable and high reducibility

The aim of this work is to show that by increasing the number of donor substituents in a donor/acceptor system, the sensitivity of the azobenzene linkage towards a reductive cleavage reaction can be enhanced to unprecedented high levels. For instance, in a triple-donor system, less than a second constitutes the half-life of the azo (NN) bond. Synthetic access to such redox active scaffolds is highly practical and requires only 1-2 synthetic steps. The fundamental molecular design is also adaptable. This is demonstrated through scaffold functionalization by azide, tetraethylene glycol, and biotin groups. The availability of the azide group is shown in a copper-free 'click' reaction suitable in context with protein conjugation and proteomics application. Finally, the clean nature of the scission process is demonstrated with the help of liquid chromatography coupled with mass analysis. This work, therefore, describes development of cleavable azobenzene linkers that can be accessed with synthetic ease, can be multiply functionalized, and show a clean and rapid response to mild reducing conditions.

Methine compounds

Methine compounds are described, which can be represented by general formula [Ic]: STR1