92-68-2

Basic information

• Product Name: 4-CYCLOHEXYLCYCLOHEXANONE
• Synonyms: 4-CYCLOHEXYLCYCLOHEXANONE;[1,1'-bicyclohexyl]-4-one;C-66;[1,1-Bi(cyclohexan)]-4-one
• CAS NO: 92-68-2
• Molecular Formula: C₁₂H₂₀O
• Molecular Weight: 180.29
• EINECS: 202-178-7
• Mol File: 92-68-2.mol
• Article Data: 17

Chemical Properties

• Melting Point: 29.2 °C
• Boiling Point: 70-72 °C(Press: 0.1 Torr)
• Appearance: /
• Density: 0.984±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-CYCLOHEXYLCYCLOHEXANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-CYCLOHEXYLCYCLOHEXANONE(92-68-2)
• EPA Substance Registry System: 4-CYCLOHEXYLCYCLOHEXANONE(92-68-2)

Safety Data

• Hazardous Substances Data: 92-68-2(Hazardous Substances Data)

Usage

General Description

4-cyclohexylcyclohexanone is an organic compound that belongs to the cyclohexanone family. It is a colorless liquid that is commonly used as a solvent for various organic reactions. This chemical is used in the production of various pharmaceuticals and agrochemicals, as well as in the synthesis of fragrance and flavor compounds. It has a variety of industrial applications, including being used as a stabilizer in the production of polymers and plastics. Additionally, 4-cyclohexylcyclohexanone is utilized as a building block in the synthesis of other organic compounds, making it an important intermediate in the chemical industry.

Upstream product

• 92-69-3 4-Phenylphenol 
• 66405-57-0 1,1'-bicyclohexyliden-4-one 
• 120982-19-6 8-Cyclohexyl-1,4-dithia-spiro[4.5]decane 
• 92-67-1 4-phenylalanine 
• 2433-14-9 bicyclohexyl-4-ol 
• 4894-75-1 1-phenyl-4-cyclohexanone 
• 20818-96-6 8-cyclohexyl-1,4-dioxaspiro[4.5]decane 
• 56309-94-5 8-(4-oxocyclohexyl)-1,4-dioxaspiro[4.5]decane 
• 7335-11-7 cis-4-cyclohexylcyclohexanol 
• 7335-42-4 trans-4-cyclohexylcyclohexanol 

Downstream Products

• 102597-04-6 2-cyclohexyl-7-methyl-1,2,3,4-tetrahydro-acridine-9-carboxylic acid 
• 103331-22-2 3,5-bis-[1]naphthylmethylene-bicyclohexyl-4-one 
• 98904-08-6 6-chloro-4'-cyclohexyl-1,1-dioxo-1,4-dihydro-2H-1λ⁶-spiro[benzo[1,2,4]thiadiazine-3,1'-cyclohexane]-7-sulfonic acid amide 
• 3363-81-3 3-<4-Cyclohexyl-cyclohex-1-enyl>-toluol; 3-Methyl-decahydro-p-terphenyl 
• 3363-80-2 4-cyclohexyl-1-p-tolyl-cyclohexene 
• 3364-98-5 2-<4-Cyclohexyl-cyclohex-1-enyl>-toluol; 2-Methyl-decahydro-p-terphenyl 
• 117372-73-3 4,4'-Dicyclohexyl-bicyclohexyl-diol-(1,1') 
• 102156-37-6 2-cyclohexyl-1,2,3,4-tetrahydro-acridine-9-carboxylic acid 
• 102662-70-4 3,5-bis-[(Ξ)-[2]thienylmethylene-bicyclohexyl-4-one 
• 1344674-35-6 (S)-3-cyclohexyl-9-(4-iodobenzyl)-2,3,4,9-tetrahydro-1H-carbazole 
• 1344674-57-2 2-([1,1'-bi(cyclohexan)]-4-ylidene)-1-(4-iodobenzyl)-1-phenylhydrazine 

Relevant articles and documents

Construction of Distant Stereocenters by Enantioselective Desymmetrizing Carbonyl-Ene Reaction

An efficient desymmetrizing carbonyl-ene reaction of 1-substituted 4-methylenecyclohexanes with glyoxal derivatives was thus executed by a chiral N,N′-dioxide/NiII catalyst, providing facile access to cyclohexene derivatives bearing two remote 1,6-related stereocenters. This distal stereocontrol methodology originates from the efficient interaction between the catalyst with enophiles, discrimination of the two chair conformations of olefinic components, and the intrinsic six-membered transition-state structure of ene process.

Synthesis and evaluations of GLP-1 secretion and anti-diabetic effect in KKAy mice of new tricyclic compounds

Glucagon-like peptide-1 (GLP-1), which belongs to the family of incretins, plays important role for the regulation of plasma glucose. Accordingly, GLP-1-based therapies for type 2 diabetes have recognized as one of the most interesting target. In this study, we have found the new tricyclic compounds having strong GLP-1 secretion from human intestinal L cells, and anti-diabetic properties in spontaneously obese and diabetic KKAy mice. The most potent compound 5ka was obtained as the unexpected product, and we would like to report the details of the synthesis, structure elucidations, pharmacological activities on secretion of GLP-1, and anti-diabetic effects using diabetic KKAy mice.

Rhodium-on-carbon catalyzed hydrogen scavenger- and oxidant-free dehydrogenation of alcohols in aqueous media

The efficient and catalytic dehydrogenation of alcohols is a clean approach for preparing carbonyl compounds accompanied only by the generation of hydrogen gas. We have accomplished the heterogeneous rhodium-on-carbon catalyzed dehydrogenation of secondary, as well as primary, alcohols to the corresponding ketones and carboxylic acids in water under basic conditions. This journal is the Partner Organisations 2014.