92000-20-9 Usage
Description
Tetrakis(4-sulfophenyl)porphine, also known as TSPP, is a water-soluble porphyrin compound that is commonly used as a photosensitizer in photodynamic therapy. It consists of a central porphyrin ring with four sulfonated phenyl groups attached, making it highly water-soluble and stable in aqueous solutions. TSPP is widely studied for its potential applications in imaging, drug delivery, and cancer treatment due to its ability to generate reactive oxygen species upon exposure to light, which can selectively kill cancer cells. Additionally, its strong absorbance in the red and near-infrared regions of the spectrum makes it suitable for deep tissue imaging and therapy. Overall, TSPP is a versatile and promising compound with diverse biomedical and research applications.
Uses
Used in Photodynamic Therapy:
Tetrakis(4-sulfophenyl)porphine is used as a photosensitizer for photodynamic therapy, where it generates reactive oxygen species upon exposure to light, selectively killing cancer cells.
Used in Imaging:
Tetrakis(4-sulfophenyl)porphine is used as an imaging agent due to its strong absorbance in the red and near-infrared regions of the spectrum, making it suitable for deep tissue imaging.
Used in Drug Delivery:
Tetrakis(4-sulfophenyl)porphine is used as a carrier in drug delivery systems, enhancing the delivery and therapeutic outcomes of various drugs.
Used in Cancer Treatment:
Tetrakis(4-sulfophenyl)porphine is used as a cancer treatment agent, where its ability to generate reactive oxygen species upon exposure to light can selectively kill cancer cells.
Used in Research:
Tetrakis(4-sulfophenyl)porphine is used in research for its potential applications in various fields, including imaging, drug delivery, and cancer treatment.
Check Digit Verification of cas no
The CAS Registry Mumber 92000-20-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,2,0,0 and 0 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 92000-20:
(7*9)+(6*2)+(5*0)+(4*0)+(3*0)+(2*2)+(1*0)=79
79 % 10 = 9
So 92000-20-9 is a valid CAS Registry Number.
92000-20-9Relevant articles and documents
Molecular organization in self-assembled binary porphyrin nanotubes revealed by resonance Raman spectroscopy
Franco, Ricardo,Jacobsen, John L.,Wang, Haorong,Wang, Zhongchun,Istvan, Krisztina,Schore, Neil E.,Song, Yujiang,Medforth, Craig J.,Shelnutt, John A.
, p. 4072 - 4077 (2010)
Porphyrin nanotubes were formed by the ionic self-assembly of tetrakis(4-sulfonatophenyl) porphyrin diacid (H4TPPS4 2-) and Sn(iv) tetra(4-pyridyl) porphyrin (Sn(OH-)(X) TPyP4+/5+ [X = OH- or H2O]) at pH 2.0. As reported previously, the tubes are hollow as revealed by transmission electron microscopy, approximately 60 nm in diameter, and can be up to several micrometres long. The absorption spectrum of the porphyrin nanotubes presents monomer-like Soret bands, as well as two additional red-shifted bands characteristic of porphyrin J-aggregates (offset face-to-face stacks). To elucidate the origin of the J-aggregate bands and the internal interactions of the porphyrins, the resonance Raman spectra have been obtained for the porphyrin nanotubes with excitations near resonance with the Soret J-aggregate band and the monomer-like bands. The resonance Raman data reveal that the Sn porphyrins are not electronically coupled to the J-aggregates within the tubes, which are formed exclusively by H4TPPS42-. This suggests that the internal structure of the nanotubes has H4TPPS 42- in aggregates that are similar to the widely studied H4TPPS42- self-aggregates and that are segregated from the Sn porphyrins. Possible internal structures of the nanotubes and mechanisms for their formation are discussed.