920283-81-4

Basic information

• Product Name: L-Proline, 1-(triphenylmethyl)-, triphenylmethyl ester
• CAS NO: 920283-81-4
• Molecular Formula: C43H37NO2
• Molecular Weight: 599.772
• Mol File: 920283-81-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: L-Proline, 1-(triphenylmethyl)-, triphenylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Proline, 1-(triphenylmethyl)-, triphenylmethyl ester(920283-81-4)
• EPA Substance Registry System: L-Proline, 1-(triphenylmethyl)-, triphenylmethyl ester(920283-81-4)

Safety Data

• Hazardous Substances Data: 920283-81-4(Hazardous Substances Data)

Upstream product

• 76-83-5 trityl chloride 
• 147-85-3 L-proline 

Downstream Products

• 1911-74-6 (S)-tritylproline 

Relevant articles and documents

TRITYLATION REACTIONS BASED ON METALLIC CATALYSIS

The invention relates to a method for preparing tritylated compounds in which protic functional groups are protected with the triphenylmethyl group, method based on the homogeneous catalysis exercised by salts or metal complexes in organic solvents. The invention relates in particular to a method for the selective tritylation of some groups, obtained both directly and by selective detritylation, with methods based on metallic catalysis. The application to amino acids, typical substrates not suitable to be subjected as such to homogeneous tritylations in organic solvents, indicates the ability of the method to extend also to hydrophilic substrates. The method allows to obtain with high yield pertrityl amino acids, N-tritylamino acids or amino acids tritylated only in lateral chain, compounds which heretofore were either difficult to obtain in aqueous solvents or obtainable through indirect methods. All, in any case, are important intermediates in peptide synthesis.